DRSC/TRiP Functional Genomics Resources

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Protein Alignment PpD5 and PPP2CB

DIOPT Version :9

Sequence 1:NP_524707.1 Gene:PpD5 / 44148 FlyBaseID:FBgn0005778 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_001009552.1 Gene:PPP2CB / 5516 HGNCID:9300 Length:309 Species:Homo sapiens


Alignment Length:300 Identity:131/300 - (43%)
Similarity:193/300 - (64%) Gaps:9/300 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 EEKNRMSQLDVIIGQLKTMAVGNRRAGNLSEATITYICQASRELFLSQPMLLELSAPVKICGDLH 81
            ::|....:||..:.||       .....|:|..:..:|:.::|:...:..:.|:..||.:|||:|
Human     2 DDKAFTKELDQWVEQL-------NECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVH 59

  Fly    82 GQFKDLLRIFQQCGVPPLSNYLFLGDYVDRGHCSIETLSLLLTYKLRYPETFFLLRGNHESADLN 146
            |||.||:.:|:..|..|.:||||:|||||||:.|:||::||:..|:||||...:|||||||..:.
Human    60 GQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQIT 124

  Fly   147 RVYGFFDECKRRY-SIKLWRSFVDCYDCMPVAAIIADRIFCVHGGLSPDLNNLDDIRRLNRPTDV 210
            :||||:|||.|:| :..:|:.|.|.:|.:|:.|::..:|||:||||||.::.||.||.|:|..:|
Human   125 QVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEV 189

  Fly   211 PSDGLLCDLLWSDPDETTGTWASNDRGVSFTFGANIVEGFLMQHKFNLIVRAHQVVEDGYEFFAD 275
            |.:|.:|||||||||: .|.|..:.||..:|||.:|.|.|...:...|:.||||:|.:||.:..|
Human   190 PHEGPMCDLLWSDPDD-RGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253

  Fly   276 RQLVTIFSAPNYCDIFDNCGAVLVVDAKLVCHFVIIRPRP 315
            |.:||||||||||....|..|::.:|..|...|:...|.|
Human   254 RNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpD5NP_524707.1 PTZ00480 19..339 CDD:185658 130/297 (44%)
MPP_superfamily 25..313 CDD:301300 128/288 (44%)
PPP2CBNP_001009552.1 MPP_PP2A_PP4_PP6 9..293 CDD:277360 129/291 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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