Protein Alignment PpD5 and PPEF1

DIOPT Version :10

• Sequence 1: NP_524707.1
• Gene: PpD5 / 44148
• FlyBaseID: FBgn0005778
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_006231.2
• Gene: PPEF1 / 5475
• HGNCID: 9243
• Length: 653
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 60/305 - (19%)
• Similarity: 107/305 - (35%)
• Gaps: 96/305 - (31%)

  Fly    66 YDAHQLLACAGNQFVLGILRAREVTPSQRLIKE--------------KTPSGE-------VEY-- 107
            |.....|.|  :::.:|:|   ::|..:....|              |||.|.       ::|
Human   266 YTIRTYLNC--DRYSIGLL---DMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREIIFYKIIDYIL 325

  Fly   108 -----INTSPKP---FWTPNVGSPSPLA--------VHHPAKEEPRQQQQQPDEQIPEVPITDEQ 156
                 ||..|.|   .||...|.|:.:|        ::.||.|....|:...||       |...
Human   326 HGKEEINVIPSPPADHWTLVSGLPTYVAENGFICNMLNAPADEYFTFQKGPVDE-------TGWV 383

  Fly   157 IAEILSGEAEVLKQHNVIGVN--FNKMIPKAGVFKQSEVFKTLNSELVQSEEEDKKWTTFLQKPS 219
            |..:||... |.|:.:::||.  :|:        |..:.|...:..:.::..:...| :.|...:
Human   384 IKNVLSLPI-VNKKEDIVGVATFYNR--------KDGKPFDEHDEHITETLTQFLGW-SLLNTDT 438

  Fly   220 RPPPKTPEERK---------LERNPP---------TERYQVRIVKQ-PKPKIAPDYKPPKSPEPE 265
            .......|.||         |.:..|         .|:..|.:::: .:.::....|     |..
Human   439 YERVNKLESRKDIAQEMVMNLTKATPDEISSILKFKEKLNVEVIEECEERQLLAILK-----EDL 498

  Fly   266 PEPEPIPMYDEYLNERQEVEVETIK---------TLVEEPVVPSE 301
            |:|....:|:...::....|.|.:|         .:||:..||.|
Human   499 PDPRTADLYEFCFSDFPITEHELVKCGLRLFLEINVVEKFKVPVE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpD5	NP_524707.1	MPP_superfamily	25..313	CDD:472684	60/305 (20%)
PPEF1	NP_006231.2	MPP_RdgC	115..452	CDD:277364	43/207 (21%)
		Catalytic	121..455		43/210 (20%)
		FRQ1	487..635	CDD:444056	13/62 (21%)
		EF-hand_7	568..636	CDD:463900
		IQ	18..37	CDD:197470