DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD5 and ppp5c

DIOPT Version :9

Sequence 1:	NP_524707.1	Gene:	PpD5 / 44148	FlyBaseID:	FBgn0005778	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001007891.1	Gene:	ppp5c / 493275	XenbaseID:	XB-GENE-982044	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	111/271 - (40%)
Similarity:	159/271 - (58%)	Gaps:	10/271 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 RELFLSQPMLLEL----SAPVKICGDLHGQFKDLLRIFQQCGVPPLSN-YLFLGDYVDRGHCSIE 117
            :::....|.|:|:    |..|.:|||.||||.||:.||...|:|..:| |:|.||:||||..|:|
Frog   211 KDILSKLPSLVEISLEKSQQVTVCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVE 275

  Fly   118 TLSLLLTYKLRYPETFFLLRGNHESADLNRVYGFFDECKRRYSIKLWRSFVDCYDCMPVAAIIAD 182
            .:..|..:||.||..|.|||||||:..:|::|||..|.|.:||.::::.|.:.:..:|:|..:..
Frog   276 VIVTLFGFKLLYPAQFHLLRGNHETDTMNQMYGFEGEVKAKYSAQMFQLFSEVFQWLPLAMCVNQ 340

  Fly   183 RIFCVHGGL-SPDLNNLDDIRRLNRPTDVPSDGLLCDLLWSDPDETTGTWASNDRGVSFTFGANI 246
            |:..:|||| |.|...||.||.:.|....|..|.:||||||||....|. :|:.||||..||.::
Frog   341 RVLIMHGGLFSEDGVTLDQIRSIERNRQPPDSGPMCDLLWSDPQPQDGR-SSSKRGVSCQFGPDV 404

  Fly   247 VEGFLMQHKFNLIVRAHQVVEDGYEFFADRQLVTIFSAPNYCDIFDNCGAVLVV---DAKLVCHF 308
            ...||.::..:.|:|:|:|..:|||...:...||:||||||||...|.||.:.:   |.|...|.
Frog   405 TRRFLEENGLDYIIRSHEVKPEGYEVSHNGLCVTVFSAPNYCDQMGNKGAYIHLNGSDLKPKFHQ 469

  Fly   309 VIIRPRPFSRP 319
            ....|.|..:|
Frog   470 FEAVPHPNVKP 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD5	NP_524707.1	PTZ00480	19..339	CDD:185658	111/271 (41%)
PpD5	NP_524707.1	MPP_superfamily	25..313	CDD:301300	108/263 (41%)
ppp5c	NP_001007891.1	PLN03088	22..>232	CDD:330826	4/20 (20%)
		TPR repeat	22..50	CDD:276809
		TPR repeat	55..85	CDD:276809
		TPR repeat	90..118	CDD:276809
		MPP_PP5_C	170..485	CDD:277362	111/271 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910