DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD5 and Ppef1

DIOPT Version :9

Sequence 1:	NP_524707.1	Gene:	PpD5 / 44148	FlyBaseID:	FBgn0005778	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_011246120.1	Gene:	Ppef1 / 237178	MGIID:	1097157	Length:	676	Species:	Mus musculus

Alignment Length:	358	Identity:	108/358 - (30%)
Similarity:	171/358 - (47%)	Gaps:	73/358 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 STGKESSKEEKNRMSQLDVIIGQLKTMAVGNRRAGNLSEATITYICQASRE------------LF 61
            :|.:||  :.|:|...|.:|  ::.....|.|....|:...|..:.||.::            ||
Mouse   113 NTRRES--QIKDRDDFLGLI--EVPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLF 173

  Fly    62 LSQPMLLEL-------SAPVK---ICGDLHGQFKDLLRIFQQCGVPPLSN-YLFLGDYVDRGHCS 115
            .::.:|.::       :.|.|   |||||||:..||:.||.:.|:|..:| |:|.||:||||:.|
Mouse   174 EARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNS 238

  Fly   116 IETLSLLLTYKLRYPETFFLLRGNHESADLNRVYGFFDECKRRYSI---KLWRSFVDCYDCMPVA 177
            :|.|.:||...|.||....|.|||||...:|..|||..|..::|.:   |:.:...:.|..:|:.
Mouse   239 MEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIG 303

  Fly   178 AIIADRIFCVHGGL--SPDLNNLDDIRRLNR---------------------------------P 207
            .||.:.|..:|||:  |.|||.|..::| |:                                 |
Mouse   304 TIIDNEILVIHGGISESTDLNTLHQLQR-NKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEP 367

  Fly   208 TDVPSDGL-------LCDLLWSDPDETTGTWASNDRGVSFTFGANIVEGFLMQHKFNLIVRAHQV 265
            ...||:.|       :.|:|||||....|.:.:..||....||.::....|.:::..:::|:|:.
Mouse   368 DKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHEC 432

  Fly   266 VEDGYEFFADRQLVTIFSAPNYCDIFDNCGAVL 298
            ..||||...|.:::|:|||.||.:...|.||.:
Mouse   433 KPDGYEVSHDGKVITVFSASNYYEEGSNRGAYI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD5	NP_524707.1	PTZ00480	19..339	CDD:185658	105/348 (30%)
PpD5	NP_524707.1	MPP_superfamily	25..313	CDD:301300	103/342 (30%)
Ppef1	XP_011246120.1	MPP_RdgC	144..479	CDD:277364	99/323 (31%)
		PTZ00183	518..660	CDD:185503
		EF-hand_7	595..663	CDD:372618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3051
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.690