DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkrn1 and SPCC1739.01

DIOPT Version :9

Sequence 1:	NP_001246867.1	Gene:	Mkrn1 / 44131	FlyBaseID:	FBgn0029152	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_588409.2	Gene:	SPCC1739.01 / 2539315	PomBaseID:	SPCC1739.01	Length:	547	Species:	Schizosaccharomyces pombe

Alignment Length:	169	Identity:	38/169 - (22%)
Similarity:	65/169 - (38%)	Gaps:	40/169 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TSSDTAISGMALGRSQTICRYYVRGICRFGELCRFSHDLSRGRPECEEQVATDVLPK-PSTSSSS 68
            |:.:......:|...:.||:|:::|.|:||..|..||.|. |........:|:.:.. .:...:|
pombe    56 TAGENCPFSHSLETERPICKYFLKGNCKFGPKCALSHALP-GNTNLPNGTSTNTMASMAANGGAS 119

  Fly    69 TIGSR-------SASISSQ-----------------QRNWANAPVFVPSQKRYTAHEQSEFETTV 109
            ::.|:       |.|:||:                 :.|.|.:|.| |..:....|..:   :|:
pombe   120 SVASKQMGANQISPSLSSKTMKNPADKANNTTATDVRGNTATSPYF-PFSRSPGRHSGN---STI 180

  Fly   110 D-----PEAVMEAQAGASYDTLAPGVSWAEVVGGPSSLN 143
            :     |..:.......|.|......|     |.|||||
pombe   181 NGMMTTPNFLSSGVNSRSVDEFNNSSS-----GFPSSLN 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkrn1	NP_001246867.1	ZnF_C3H1	20..43	CDD:214632	10/22 (45%)
Mkrn1	NP_001246867.1	RING	213..267	CDD:238093
SPCC1739.01	NP_588409.2	ZnF_C3H1	43..67	CDD:214632	1/10 (10%)
		ZnF_C3H1	72..92	CDD:214632	8/19 (42%)
		YTH1	86..379	CDD:227416	29/139 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11224
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000