DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkrn1 and F54B11.5

DIOPT Version :9

Sequence 1:	NP_001246867.1	Gene:	Mkrn1 / 44131	FlyBaseID:	FBgn0029152	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_510276.1	Gene:	F54B11.5 / 186213	WormBaseID:	WBGene00010028	Length:	201	Species:	Caenorhabditis elegans

Alignment Length:	172	Identity:	39/172 - (22%)
Similarity:	62/172 - (36%)	Gaps:	54/172 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 SWAEVVGGPSSLNK---------EDY-------------GEEN-------SSCAWGEFSAYPI-H 165
            :|.|.:.....:|:         |:|             |.||       ..|...:.|...: :
Worm    16 TWDEFLADIKEMNRNYRSLLVENEEYLAFALRNIDYQREGYENWKSEIKILCCKVNQMSKQVLNY 80

  Fly   166 MELC--EMCDQYCLHPTDQVQRRSHNRECLQQHEQAMELS-FAIARSKD--KTCGICFDTIMEKA 225
            .||.  |....|.||     :....|:|..::....|..| |.:.::.|  ..|.||.:.|.:.
Worm    81 KELTFREFLSTYDLH-----KLMITNKESRKRSVDPMSTSQFILTQTSDVEGNCVICMENINDL- 139

  Fly   226 GREKRFGILPNCNHIFCLECIRTWRQAKQFENKITRACPECR 267
                   :|| |.|.||:.||     |.:.|.:...:||.|:
Worm   140 -------LLP-CLHAFCIRCI-----ANEMEYRHDFSCPICK 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkrn1	NP_001246867.1	ZnF_C3H1	20..43	CDD:214632
Mkrn1	NP_001246867.1	RING	213..267	CDD:238093	16/53 (30%)
F54B11.5	NP_510276.1	COG5540	<83..174	CDD:227827	28/105 (27%)
		RING_Ubox	129..168	CDD:388418	16/52 (31%)
		RING-HC finger (C3HC4-type)	129..167	CDD:319361	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900