DRSC/TRiP Functional Genomics Resources

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Protein Alignment hbs and Kirrel3

DIOPT Version :9

Sequence 1:NP_001286439.1 Gene:hbs / 44129 FlyBaseID:FBgn0029082 Length:1235 Species:Drosophila melanogaster
Sequence 2:XP_006510620.1 Gene:Kirrel3 / 67703 MGIID:1914953 Length:803 Species:Mus musculus


Alignment Length:786 Identity:175/786 - (22%)
Similarity:287/786 - (36%) Gaps:189/786 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 VQKFHLTPHDLQILEGTDTLLRCEVSNRAGKVQWTKDGFALGFSAVIPGFPRYSVLVDAKQNAYN 102
            |..|...|.|..::.|....|.|.:....|.|.|.|||.|||....:..:|:|.|:.:.....::
Mouse    47 VYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHH 111

  Fly   103 LQIKNATLEDDAEYQCQVGPAAGNPAIRAN-AKLSIVAAPSSIVIEGYARNARVEVEERQNLTLH 166
            |:|..|.|:|||.|:||    |...|||:. |:|:::..|...:|.|   ...:.:.....|.|.
Mouse   112 LKILRAELQDDAVYECQ----AIQAAIRSRPARLTVLVPPDDPIILG---GPVISLRAGDPLNLT 169

  Fly   167 CIAENANPAAEIVWF-QGEVPVSTAPIVTVNQTA---PKRFTTSSTLHLQPRAEDDYKEFSCEAR 227
            |.|:||.|||.|:|. :||| ::.|   |.::|.   .||.:..|||.:.|...::.:...|.|.
Mouse   170 CHADNAKPAASIIWLRKGEV-INGA---TYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRAT 230

  Fly   228 HKALPPDVPMRAQVQLSVLYPP-------GAPFFEGYSQGETLHRGQEVQIACRSRGGNPPAQLT 285
            :||:|..  ....|.:.:.:||       ..|..|  ....|.|        |.::......|..
Mouse   231 NKAIPGG--KETSVTIDIQHPPLVNLSVEPQPVLE--DNIVTFH--------CSAKANPAVTQYR 283

  Fly   286 WYRNGVAISSPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVY 350
            |.:.|..|   :..||.|......:|..:|.    :.||..|.|.:|.|...::  |.:.|:...
Mouse   284 WAKRGHII---KEASGELYRTTVDYTYFSEP----VSCEVTNALGSTNLSRTVD--VYFGPRMTS 339

  Fly   351 LSGANQAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDS- 414
            ...:....:|.....||... .||...|.|...|               .|.|.|:..:||:.| 
Mouse   340 EPQSLLVDLGSDAVFSCAWI-GNPSLTIVWMKRG---------------SGVVLSNEKTLTLKSV 388

  Fly   415 -QSRTFIAVCHAL-------NTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCS 471
             |......||.|:       ..|:|..|.|           ||:::.......| .|...:::|.
Mouse   389 RQEDAGKYVCRAVVPRVGAGEREVTLTVNG-----------PPIISSTQTQHAL-HGEKGQIKCF 441

  Fly   472 SAGGNPPPTLQWYKNDKIINAPSK---LVDSKITSE-------LSLLVNASDNNAIYKCKVQNA- 525
            .....||..:.|...:.::.:.:.   .|::..|.|       :|.:|.| |...||.|...|: 
Mouse   442 IRSTPPPDRIAWSWKENVLESGTSGRYTVETVNTEEGVISTLTISNIVRA-DFQTIYNCTAWNSF 505

  Fly   526 AIDIPLFATKTLGVHFPPET-VKISVVPKNLVPGI-----------RAKLI--CDSSSSNPPAKI 576
            ..|..:...|..|....... ::...||..::.|:           .|.::  |.:.|..     
Mouse   506 GSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQR----- 565

  Fly   577 SWWKDGIPVEGLNLANRPGLWG-GSVSTLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETIS--- 637
                        :...|||:.| |:.....:.:....:|.|:|   .:.|::....||:..|   
Mouse   566 ------------STGGRPGISGRGTEKKARLRLPRRANLKGVV---SAKNDIRVEIVHKEPSSGR 615

  Fly   638 --------------------------LDILYPPK------------------FETPQSTTFVGVE 658
                                      |::|...:                  |:...||..:.:.
Mouse   616 EAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLS 680

  Fly   659 GAPFHVELLASGNPMVITYTWTKDGLPISS--NSLSGQ-RLISDGPRLNISRLSRNDAGVYICEA 720
            ..  ..:|..:|...|.|      |:..::  ::|||| ||...|.|.   .|....:.:.:||.
Mouse   681 SC--QPDLRPTGKQRVPT------GMSFTNIYSTLSGQGRLYDYGQRF---VLGMGSSSIELCER 734

  Fly   721 LNSQGT 726
            ...:|:
Mouse   735 EFQRGS 740

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbsNP_001286439.1 Ig 44..122 CDD:299845 27/77 (35%)
IG_like 45..137 CDD:214653 33/92 (36%)
Ig 153..231 CDD:299845 26/81 (32%)
IG_like 258..342 CDD:214653 18/83 (22%)
Ig 266..327 CDD:299845 12/60 (20%)
IG_like 357..>414 CDD:214653 13/56 (23%)
Ig 360..427 CDD:299845 18/75 (24%)
Ig <468..526 CDD:299845 15/68 (22%)
I-set 547..633 CDD:254352 15/99 (15%)
Ig 556..631 CDD:299845 13/88 (15%)
I-set 644..735 CDD:254352 20/104 (19%)
IGc2 668..725 CDD:197706 15/59 (25%)
IG_like 751..829 CDD:214653
IGc2 753..815 CDD:197706
Ig 852..928 CDD:143165
FN3 935..1017 CDD:238020
Kirrel3XP_006510620.1 IG_like 54..143 CDD:214653 33/92 (36%)
Ig strand A' 56..60 CDD:409353 1/3 (33%)
Ig strand B 64..71 CDD:409353 2/6 (33%)
Ig strand C 78..82 CDD:409353 2/3 (67%)
Ig strand C' 84..87 CDD:409353 1/2 (50%)
Ig strand D 97..101 CDD:409353 2/3 (67%)
Ig strand E 104..116 CDD:409353 2/11 (18%)
Ig strand G 132..143 CDD:409353 5/10 (50%)
IgI_2_KIRREL3-like 149..246 CDD:409416 31/105 (30%)
Ig strand B 166..170 CDD:409416 2/3 (67%)
Ig strand C 180..184 CDD:409416 1/3 (33%)
Ig strand E 210..214 CDD:409416 3/3 (100%)
Ig strand F 224..229 CDD:409416 1/4 (25%)
Ig strand G 239..242 CDD:409416 0/2 (0%)
Ig <267..334 CDD:416386 19/83 (23%)
Ig strand B 267..274 CDD:409353 3/14 (21%)
Ig strand C 279..286 CDD:409353 2/6 (33%)
Ig strand C' 288..291 CDD:409353 1/2 (50%)
Ig strand D 298..302 CDD:409353 1/3 (33%)
Ig strand E 304..310 CDD:409353 1/5 (20%)
Ig strand G 321..334 CDD:409353 3/14 (21%)
Ig 335..416 CDD:416386 21/96 (22%)
Ig strand A' 343..347 CDD:409353 0/3 (0%)
Ig strand B 350..360 CDD:409353 2/10 (20%)
Ig strand C 365..371 CDD:409353 2/5 (40%)
Ig strand E 381..387 CDD:409353 2/5 (40%)
IgI_5_KIRREL3 418..515 CDD:409479 21/109 (19%)
Ig strand B 436..440 CDD:409479 0/3 (0%)
Ig strand C 450..454 CDD:409479 0/3 (0%)
Ig strand E 481..485 CDD:409479 0/3 (0%)
Ig strand F 496..501 CDD:409479 3/4 (75%)
Ig strand G 509..512 CDD:409479 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D141865at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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