Protein Alignment hbs and F11R

DIOPT Version :10

• Sequence 1: NP_788355.1
• Gene: hbs / 44129
• FlyBaseID: FBgn0287864
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_001369656.1
• Gene: F11R / 50848
• HGNCID: 14685
• Length: 327
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 76/348 - (21%)
• Similarity: 119/348 - (34%)
• Gaps: 87/348 - (25%)

  Fly    13 LATTICHV-MAAVTAPTPAAQVAAPPVQKFHLTPHDLQILEGTDTLLRCEVSN-RAGKVQWTKDG 75
            ||..:|.: :.:||.               |.:..:::|.|.....|.|..|. .:.:|:|..|
Human    17 LAILLCSLALGSVTV---------------HSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFD- 65

  Fly    76 FALGFSAVIPGFPRYSVLVDAKQNA----------YNLQIKNATLEDDAEYQCQVGPAAGNPAIR 130
                     .|.....|..:.|..|          ..:..|:.|.||...|.|.|....||....
Human    66 ---------QGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGE 121

  Fly   131 ANAKLSIVAAPSSIVIEGYARNARVEVEERQNLTLHCIAENANPAAEIVWFQGEVPVSTAPIVTV 195
            ...||.::..||...:     |............|.|..::.:|.:|..||:..:.:.|.|..|
Human   122 VKVKLIVLVPPSKPTV-----NIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKST- 180

  Fly   196 NQTAPKRFTTSS--------TLHLQPRAEDDYKEFSCEARH-------------KALPPDVPMRA 239
                 :.|:.||        .|...|.:..|..|:|||||:             :|:..:|.:..
Human   181 -----RAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIV 240

  Fly   240 QVQLSVLYPPGAPFFE---GYSQGETLHRG------QEVQIACRSRGGNPPAQLTWYRNG----- 290
            ...|..|...|...|.   .||:|.....|      ....:.|.:...:|.:.|:..:.|
Human   241 AAVLVTLILLGILVFGIWFAYSRGHFDKLGACPSIFPSHAVFCPADTHDPISSLSGTKKGTSSKK 305

  Fly   291 VAISSPQRTSGRLSENVYKFTAA 313
            |..|.|   |.| ||..:|.|::
Human   306 VIYSQP---SAR-SEGEFKQTSS 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbs	NP_788355.1	IG_like	45..137	CDD:214653	23/102 (23%)
		Ig strand B	56..60	CDD:409353	1/3 (33%)
		Ig strand C	68..72	CDD:409353	1/3 (33%)
		Ig strand E	91..105	CDD:409353	3/23 (13%)
		Ig strand F	115..120	CDD:409353	2/4 (50%)
		Ig strand G	128..131	CDD:409353	0/2 (0%)
		Ig	162..232	CDD:472250	22/90 (24%)
		Ig strand B	162..167	CDD:409353	1/4 (25%)
		Ig strand C	177..181	CDD:409353	1/3 (33%)
		Ig strand E	207..211	CDD:409353	2/11 (18%)
		Ig strand F	221..226	CDD:409353	3/4 (75%)
		Ig	246..342	CDD:472250	20/82 (24%)
		Ig strand B	269..273	CDD:409353	0/3 (0%)
		Ig strand C	283..287	CDD:409353	1/3 (33%)
		Ig strand F	320..325	CDD:409353
		Ig strand G	335..338	CDD:409353
		Ig	343..431	CDD:472250
		Ig strand B	363..367	CDD:409353
		Ig strand C	377..381	CDD:409353
		Ig strand E	406..410	CDD:409353
		Ig strand F	420..425	CDD:409353
		Ig	443..527	CDD:472250
		Ig strand B	466..470	CDD:409353
		Ig strand C	480..484	CDD:409353
		Ig strand E	503..507	CDD:409353
		Ig strand F	517..522	CDD:409353
		Ig	554..640	CDD:472250
		Ig strand B	561..565	CDD:409353
		Ig strand C	575..579	CDD:409353
		Ig strand E	602..608	CDD:409353
		Ig strand F	618..623	CDD:409353
		Ig strand G	633..636	CDD:409353
		Ig_3	643..722	CDD:464046
		Ig	748..829	CDD:472250
		Ig strand B	756..760	CDD:409353
		Ig strand C	769..775	CDD:409353
		Ig strand E	792..798	CDD:409353
		Ig strand F	808..813	CDD:409353
		Ig strand G	822..825	CDD:409353
		Ig_3	833..918	CDD:464046
		FN3	<932..1151	CDD:442628
		FN3	935..1017	CDD:238020
F11R	NP_001369656.1	IgV_1_JAM1-like	30..129	CDD:409538	25/123 (20%)
		FR1	30..52	CDD:409538	6/36 (17%)
		Ig strand A	30..33	CDD:409538	1/17 (6%)
		Ig strand A'	37..41	CDD:409538	0/3 (0%)
		Ig strand B	44..53	CDD:409538	2/8 (25%)
		CDR1	53..58	CDD:409538	1/4 (25%)
		Ig strand C	58..66	CDD:409538	3/17 (18%)
		FR2	59..66	CDD:409538	3/16 (19%)
		CDR2	69..83	CDD:409538	3/13 (23%)
		Ig strand C'	69..74	CDD:409538	0/4 (0%)
		Ig strand C'	77..79	CDD:409538	0/1 (0%)
		FR3	84..112	CDD:409538	6/27 (22%)
		Ig strand D	86..90	CDD:409538	0/3 (0%)
		Ig strand E	92..96	CDD:409538	0/3 (0%)
		Ig strand F	105..113	CDD:409538	3/7 (43%)
		CDR3	113..119	CDD:409538	2/5 (40%)
		Ig strand G	119..128	CDD:409538	2/8 (25%)
		FR4	120..129	CDD:409538	2/8 (25%)
		IgI_2_JAM1	135..231	CDD:409542	22/106 (21%)
		Ig strand A	135..139	CDD:409542	0/8 (0%)
		Ig strand A'	141..144	CDD:409542	0/2 (0%)
		Ig strand B	147..155	CDD:409542	2/7 (29%)
		Ig strand C	163..168	CDD:409542	2/4 (50%)
		Ig strand C'	170..172	CDD:409542	0/1 (0%)
		Ig strand D	187..191	CDD:409542	1/3 (33%)
		Ig strand E	195..199	CDD:409542	1/3 (33%)
		Ig strand F	208..214	CDD:409542	3/5 (60%)
		Ig strand G	221..231	CDD:409542	0/9 (0%)