Protein Alignment hbs and kirrel1a

DIOPT Version :9

• Sequence 1: NP_001286439.1
• Gene: hbs / 44129
• FlyBaseID: FBgn0029082
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_001349348.1
• Gene: kirrel1a / 405804
• ZFINID: ZDB-GENE-040426-2126
• Length: 819
• Species: Danio rerio
• Alignment Length: 1049
• Identity: 233/1049 - (22%)
• Similarity: 358/1049 - (34%)
• Gaps: 345/1049 - (32%)

  Fly    40 KFHLTPHDLQILEGTDTLLRCEVSNRAGKVQWTKDGFALGFSAVIPGFPRYSV--LVDAKQNAYN 102
            :|...|.|..::.|...:|.|.|.|.:|.|||||||.|||....:..:|||.|  |||..|  ||
Zfish    21 RFSQEPADQSVVLGQRVVLSCVVFNYSGIVQWTKDGLALGIGEDLRAWPRYRVLRLVDVGQ--YN 83

  Fly   103 LQIKNATLEDDAEYQCQVGPAAGNPAIRA-NAKLSIVAAPSSIVIEGYARNARVEVEERQNLTLH 166
            |:|..|.|.||:.|:||    |...|:|: .|||:::..|...||||   :..:.:.......:.
Zfish    84 LEISAAELSDDSLYECQ----ATEAALRSRRAKLTVLIPPDEPVIEG---SPEILLTAGVPYNMS 141

  Fly   167 CIAENANPAAEIVWFQGEVPVSTAPIVTVNQTAP--KRFTTSSTLHLQPRAEDDYKEFSCEARHK 229
            |::..|.||:.|.|.:..:|:..|  |:..:..|  ||.||.|.|.:||...|..|.|:|.|.:.
Zfish   142 CVSRGAKPASVIEWQKDGLPIEGA--VSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNL 204

  Fly   230 ALPPDVPMRAQVQLSVLYPPGAPFFEGYSQGETLHRGQEVQIACRSRGGNPPAQLTWYRNGVAIS 294
            |:|  :..||.:.|:|.:||....   ..:..::..|:.|...|::....|.....|.:.||.|.
Zfish   205 AVP--MGKRATITLNVHHPPVVTL---SIEPRSVLEGERVTFTCQATANPPIMGYKWAKGGVVIQ 264

  Fly   295 SPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAKV 359
            ..:       |:|:             |.:|.:...|.|:..::
Zfish   265 GAR-------ESVF-------------VTKADHSFFTEPVSCQV--------------------- 288

  Fly   360 GDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFIAVCH 424
                                  .|.                  |.|:|:|:.:|......:.|
Zfish   289 ----------------------FNA------------------VGSTNVSILVDVHFGPILVV-- 311

  Fly   425 ALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKNDKI 489
                                .|.|  :|...|.|:       .|.|..| ||||.||.|.|..
Zfish   312 --------------------EPKP--VTVDVDSDV-------TLNCKWA-GNPPLTLTWTKKG-- 344

  Fly   490 INAPSKLVDSKITSELSLLVNASDNNAIYKCKVQNAAIDIPLFATK-------------TLGVHF 541
                |.:|             .|:||.:|...|..|  |...:..|             ||.|:.
Zfish   345 ----SSMV-------------LSNNNQLYLKSVSQA--DAGQYVCKAIVPRIGVGETEVTLTVNG 390

  Fly   542 PPETVKISVVP-KNLVPGIRAKLICDSSSSNPPAKISW-WKDGI------------PVEGLNLAN 592
            ||   .||..| :..|.|.|.::.|..:|:.||.||.| ||:.:            .||    .:
Zfish   391 PP---IISSEPFQYAVRGERGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVE----QS 448

  Fly   593 RPGLWGGSV-STLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFETPQSTTFVG 656
            :|...||:| |||.:. ||.:......|.|.:.|.....::  .|||:                .
Zfish   449 KPSAQGGAVLSTLTIN-NIMESDFQSTYNCTAWNSFGSGTM--IISLE----------------E 494

  Fly   657 VEGAPFHVELLASGNP-------------MVITYTWTKDGLPISSNSLSGQRLISDG-PRLNISR 707
            :|..|  |.::|.|..             ::..|...|          ..:|.::.| |.:.:..
Zfish   495 MEIVP--VGIIAGGTVGCSILLLLCLLALVLFLYRQRK----------GSRRGVTLGKPDIKVET 547

  Fly   708 LSRNDAGVYICEALNSQGTALLEIQVAVEYAPTITAVSEGRSFVAGEPAVLACHIQARPLEAAHV 772
            :::....:.  |...|..||...::....:.|::|.....:.|  .:...|...:::..|:
Zfish   548 INKESHSLE--EDSGSVSTATRMVKAMYSFLPSVTLSPSSQPF--KDDIDLKQELRSDTLD---- 604

  Fly   773 RWSRDGYDLATRT-------ISSFENGTALLQIASVERSDI------GNFTCIVDNQRGAPAAQN 824
              :|..|:|...|       .|:.:.|....:  |:..||.      |....:|.:..|.|
Zfish   605 --TRQDYELKDPTNGYYNVRASTHDEGRPASR--SMHYSDYRTSSQPGGAAAVVSSSSGPP---- 661

  Fly   825 VLLVVQTAPEIDHSPGFTRYAARLGVRAQLICRSLASPQPSFIWRRHGKDLKMQRRNKFKSVERQ 889
                    |.....|| |..:...|.||     ....|:|.
Zfish   662 --------PGATAGPG-TPSSLAPGSRA-----GCYDPRPP------------------------ 688

  Fly   890 VDALNFESALLIENTSPDDYGQYECVVRNSLGQASTTLEFSKPSRPDAPLQLRVGNVSDTGVDLN 954
                        ...|.:.|.|:....|  .||:......|.|...|.|.:..:  :..:|
Zfish   689 ------------SRLSHNSYAQFNTFTR--AGQSQQPPPGSGPQTSDFPAECSL--LDSSG---- 733

  Fly   955 WTPGFDGGMQTYFRLRLKQHGEDKYKYVDAKP----GHQNISLDGLKPGATY-YFSVMAANEAGG 1014
                              |.|.:.|.|....|    |....||..|:.|..| .:.|..:..|||
Zfish   734 ------------------QLGYENYGYPSHYPTFRMGFAPPSLAPLEGGPAYEMYGVGPSVGAGG 780

  Fly  1015 SKFMPDIKL 1023
            ....|:..|
Zfish   781 GAGTPETGL 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbs	NP_001286439.1	Ig	44..122	CDD:299845	37/79 (47%)
		IG_like	45..137	CDD:214653	43/94 (46%)
		Ig	153..231	CDD:299845	23/79 (29%)
		IG_like	258..342	CDD:214653	14/83 (17%)
		Ig	266..327	CDD:299845	12/60 (20%)
		IG_like	357..>414	CDD:214653	5/56 (9%)
		Ig	360..427	CDD:299845	7/66 (11%)
		Ig	<468..526	CDD:299845	18/57 (32%)
		I-set	547..633	CDD:254352	29/100 (29%)
		Ig	556..631	CDD:299845	26/88 (30%)
		I-set	644..735	CDD:254352	14/104 (13%)
		IGc2	668..725	CDD:197706	9/70 (13%)
		IG_like	751..829	CDD:214653	15/90 (17%)
		IGc2	753..815	CDD:197706	13/74 (18%)
		Ig	852..928	CDD:143165	9/75 (12%)
		FN3	935..1017	CDD:238020	18/86 (21%)
kirrel1a	NP_001349348.1	I-set	21..115	CDD:333254	44/99 (44%)
		Ig2_KIRREL3-like	137..218	CDD:143236	28/84 (33%)
		I-set	222..303	CDD:333254	20/164 (12%)
		Ig_3	307..372	CDD:316449	26/117 (22%)
		Ig5_KIRREL3	390..493	CDD:143306	33/112 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141865at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920