DRSC/TRiP Functional Genomics Resources

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Protein Alignment hbs and CG17716

DIOPT Version :9

Sequence 1:NP_001286439.1 Gene:hbs / 44129 FlyBaseID:FBgn0029082 Length:1235 Species:Drosophila melanogaster
Sequence 2:NP_001286391.1 Gene:CG17716 / 36521 FlyBaseID:FBgn0000633 Length:822 Species:Drosophila melanogaster


Alignment Length:738 Identity:165/738 - (22%)
Similarity:245/738 - (33%) Gaps:260/738 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   147 EGYARNARVEVEERQNLTLHCIAENANPAAEIVWFQGEVPVSTAPIVTV-NQTAPKRFTTSSTLH 210
            |...|..|...|:..:..|...:..:...|.....|.....|:|...:| |:|..||  ..||||
  Fly   111 EARQRQRRETEEDELDAVLRAPSSTSTSTAVATTVQATSSSSSATRSSVINETKAKR--PRSTLH 173

  Fly   211 L-----QPRAE------DDYKEFSC----------EARHKA------------------LPPDVP 236
            |     ||:.:      ||.:||..          ::|.:|                  :||: |
  Fly   174 LAPEDMQPKPKEPVIIIDDVEEFDSGTSTSDLIARKSREEAEEEEDEGPLEPRVLPLRPVPPN-P 237

  Fly   237 MRAQVQLSVLYPPGAPFFEGYSQGETLHRGQEVQIACRSRGGNPPAQLTWYRNGVAISSPQRTSG 301
            ..|: ::||:|.      |.:|         |:::.|..  ....|...||:||..:.:..||: 
  Fly   238 YEAE-EMSVVYA------EQHS---------EIKLMCEV--DLDIATSMWYKNGQVVHAMDRTA- 283

  Fly   302 RLSENVYKFTAAA-----------EDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGAN 355
            |:::  |:|...|           ||:| ...|||:|....|.....:.|.||..||..||    
  Fly   284 RVTD--YRFIKEANGALTITNVMLEDDG-KWQCEAENTRRYTENARPVKLVVLDRPKPPYL---- 341

  Fly   356 QAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFI 420
                                     .|:.|.||                :||:.:.:...|.   
  Fly   342 -------------------------LIDSRRLD----------------ASNLFVPVKENSE--- 362

  Fly   421 AVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQW-- 483
                                                         |.|.|.|.||||.|||.|  
  Fly   363 ---------------------------------------------LNLACVSEGGNPRPTLTWEV 382

  Fly   484 ----------------------YKNDKIINAPSKLVDSKITSELSL-LVNASDNNAIYKCKVQNA 525
                                  .|.:|:.....| ::|...||..| .|..:.:||...|.:::.
  Fly   383 LLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYK-INSGAKSEARLPAVYRAHHNARILCVMEHP 446

  Fly   526 AIDIPLFATKTLGVHFPPETVKISVVPKNLVP---GIRAKLICDSSSSNPPAKISWWKDG----I 583
            .:.|...|:..|.|.:.| :..||..|....|   ||...|.|| ..||||:...|.||.    :
  Fly   447 TLKIRQNASLLLDVQYTP-SFAISRTPGFGYPLREGIEVSLKCD-VDSNPPSTPRWQKDDGDTPV 509

  Fly   584 PVEGLNLANRPGLWGGSVSTLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFET 648
            |..|....|              :.:|.::..| .|.|.|.:...|.|     |:......:|::
  Fly   510 PQTGDGFLN--------------FTSIRREHSG-WYKCTSRHLNFQYS-----SIGYYLSVRFDS 554

  Fly   649 PQSTTFVGVEGAPFHVEL---LASGNPM----------VITYTWTKDGL-------PISSNSLSG 693
                  |.|...|...::   .||.||.          .:|....:..|       |||:. |.|
  Fly   555 ------VDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQCPQGSLGCWSHLDPISAR-LRG 612

  Fly   694 QRLISDGP--RLNISRLSRNDAGVYICEALNSQGTALLE----IQVAVEYAPTITAVSEGRSFVA 752
            ....|..|  :.::..:...|||:|.|...:......||    :.|:|:.|||:.|::.......
  Fly   613 LGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQSVTVSVKGAPTVMALNATPVAYP 677

  Fly   753 GEPAVLACHIQARPLEAAH-VRW 774
            |.|..|.....|.|  .|| .||
  Fly   678 GSPLHLNVEFCANP--PAHAARW 698

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbsNP_001286439.1 Ig 44..122 CDD:299845
IG_like 45..137 CDD:214653
Ig 153..231 CDD:299845 25/117 (21%)
IG_like 258..342 CDD:214653 23/94 (24%)
Ig 266..327 CDD:299845 19/71 (27%)
IG_like 357..>414 CDD:214653 6/56 (11%)
Ig 360..427 CDD:299845 7/66 (11%)
Ig <468..526 CDD:299845 22/82 (27%)
I-set 547..633 CDD:254352 26/92 (28%)
Ig 556..631 CDD:299845 22/81 (27%)
I-set 644..735 CDD:254352 25/116 (22%)
IGc2 668..725 CDD:197706 18/75 (24%)
IG_like 751..829 CDD:214653 9/25 (36%)
IGc2 753..815 CDD:197706 9/23 (39%)
Ig 852..928 CDD:143165
FN3 935..1017 CDD:238020
CG17716NP_001286391.1 IG_like 244..332 CDD:214653 27/108 (25%)
Ig 254..323 CDD:143165 19/74 (26%)
Ig 359..452 CDD:299845 25/141 (18%)
Ig_3 477..536 CDD:290638 21/74 (28%)
IG_like 479..550 CDD:214653 23/91 (25%)
IG_like 578..660 CDD:214653 17/82 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11640
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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