Protein Alignment hbs and CADM1

DIOPT Version :10

• Sequence 1: NP_788355.1
• Gene: hbs / 44129
• FlyBaseID: FBgn0287864
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: XP_016872946.1
• Gene: CADM1 / 23705
• HGNCID: 5951
• Length: 477
• Species: Homo sapiens
• Alignment Length: 74
• Identity: 18/74 - (24%)
• Similarity: 29/74 - (39%)
• Gaps: 14/74 - (18%)

  Fly   127 VLEESFTD--KIITTYRDDPDLQNLIDFAQQEFHCCGLSNEGYLDWGKNEYFNCSSPSVEKCGVP 189
            :||:...|  |.:....||.|:      |..:..   ||.:..:...|::|.   :|..:|....
Human   650 ILEKLLKDKRKELGPLPDDDDM------ASPKLK---LSRKSGVSPKKSKYM---TPMQQKLNEV 702

  Fly   190 YSCCINATD 198
            |....|.||
Human   703 YEAVKNYTD 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbs	NP_788355.1	IG_like	45..137	CDD:214653	4/11 (36%)
		Ig strand B	56..60	CDD:409353
		Ig strand C	68..72	CDD:409353
		Ig strand E	91..105	CDD:409353
		Ig strand F	115..120	CDD:409353
		Ig strand G	128..131	CDD:409353	2/2 (100%)
		Ig	162..232	CDD:472250	10/37 (27%)
		Ig strand B	162..167	CDD:409353	2/4 (50%)
		Ig strand C	177..181	CDD:409353	0/3 (0%)
		Ig strand E	207..211	CDD:409353
		Ig strand F	221..226	CDD:409353
		Ig	246..342	CDD:472250
		Ig strand B	269..273	CDD:409353
		Ig strand C	283..287	CDD:409353
		Ig strand F	320..325	CDD:409353
		Ig strand G	335..338	CDD:409353
		Ig	343..431	CDD:472250
		Ig strand B	363..367	CDD:409353
		Ig strand C	377..381	CDD:409353
		Ig strand E	406..410	CDD:409353
		Ig strand F	420..425	CDD:409353
		Ig	443..527	CDD:472250
		Ig strand B	466..470	CDD:409353
		Ig strand C	480..484	CDD:409353
		Ig strand E	503..507	CDD:409353
		Ig strand F	517..522	CDD:409353
		Ig	554..640	CDD:472250
		Ig strand B	561..565	CDD:409353
		Ig strand C	575..579	CDD:409353
		Ig strand E	602..608	CDD:409353
		Ig strand F	618..623	CDD:409353
		Ig strand G	633..636	CDD:409353
		Ig_3	643..722	CDD:464046
		Ig	748..829	CDD:472250
		Ig strand B	756..760	CDD:409353
		Ig strand C	769..775	CDD:409353
		Ig strand E	792..798	CDD:409353
		Ig strand F	808..813	CDD:409353
		Ig strand G	822..825	CDD:409353
		Ig_3	833..918	CDD:464046
		FN3	<932..1151	CDD:442628
		FN3	935..1017	CDD:238020
CADM1	XP_016872946.1	IgV_1_Necl-2	53..146	CDD:409465
		FR1	53..71	CDD:409465
		Ig strand A	53..55	CDD:409465
		Ig strand A'	56..62	CDD:409465
		Ig strand B	64..72	CDD:409465
		CDR1	72..77	CDD:409465
		FR2	78..85	CDD:409465
		Ig strand C	78..84	CDD:409465
		CDR2	86..97	CDD:409465
		Ig strand C'	88..92	CDD:409465
		Ig strand C'	94..97	CDD:409465
		FR3	98..133	CDD:409465
		Ig strand D	102..109	CDD:409465
		Ig strand E	112..118	CDD:409465
		Ig strand F	125..133	CDD:409465
		CDR3	134..137	CDD:409465
		Ig strand G	137..146	CDD:409465
		FR4	139..146	CDD:409465
		IgI_2_Necl-2	147..245	CDD:409466
		Ig strand A	147..150	CDD:409466
		Ig strand A'	153..157	CDD:409466
		Ig strand B	166..176	CDD:409466
		Ig strand C	179..188	CDD:409466
		Ig strand C'	189..192	CDD:409466
		Ig strand D	194..201	CDD:409466
		Ig strand E	204..214	CDD:409466
		Ig strand F	222..230	CDD:409466
		Ig strand G	237..244	CDD:409466
		IG_like	258..336	CDD:214653
		Ig strand B	269..273	CDD:409353
		Ig strand C	282..287	CDD:409353
		Ig strand E	301..306	CDD:409353
		Ig strand F	316..321	CDD:409353
		Ig strand G	329..332	CDD:409353
		4.1m	430..448	CDD:128590