DRSC/TRiP Functional Genomics Resources

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Protein Alignment hbs and kirrel1

DIOPT Version :9

Sequence 1:NP_001286439.1 Gene:hbs / 44129 FlyBaseID:FBgn0029082 Length:1235 Species:Drosophila melanogaster
Sequence 2:XP_012808656.1 Gene:kirrel1 / 100489692 XenbaseID:XB-GENE-483274 Length:754 Species:Xenopus tropicalis


Alignment Length:560 Identity:149/560 - (26%)
Similarity:233/560 - (41%) Gaps:93/560 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 TAPTPAAQVAAPPVQKFHLTPHDLQILEGTDTLLRCEVSNRAGKVQWTKDGFALGFSAVIPGFPR 89
            |.|...:|...|   :|...|.|..::.|...:|.|.|.|.:|.|||||||.|||....:..:||
 Frog    10 TLPETLSQAFQP---RFIQEPTDQTVVAGQKVVLTCVVLNYSGIVQWTKDGLALGLGQNLRIWPR 71

  Fly    90 YSVLVDAKQNAYNLQIKNATLEDDAEYQCQVGPAAGNPAIRA-NAKLSIVAAPSSIVIEGYARNA 153
            |.::.:.:...|||:|.||::.|||.::||    |...|:|: .|||:::..|...|||| ....
 Frog    72 YQIVGNVESGQYNLEISNASIVDDANFECQ----ATEAALRSQKAKLTVLIPPEDPVIEG-GPEI 131

  Fly   154 RVEVEERQNLTLHCIAENANPAAEIVWFQ------GEVPVSTAPIVTVNQTAPKRFTTSSTLHLQ 212
            .:......|||  |.|.:|.|.|.||||:      |:| .||..:..     .||.||.|.|.:.
 Frog   132 LLRAGTPTNLT--CRANSAKPPASIVWFRDGNQQAGDV-YSTEVLAD-----GKRATTVSYLLIS 188

  Fly   213 PRAEDDYKEFSCEARHKALPPDVPMRAQVQLSVLYPPGAPFFEGYSQGETLHRGQEVQIACRSRG 277
            |..:|..:.|:|...::|:|..  ....|:|:|.:||....   ....:|:..|:.|:..| |..
 Frog   189 PTDQDIGRVFTCRTSNEAIPSG--KETSVKLNVHHPPTVTL---SIHPQTVQEGERVRFTC-SAT 247

  Fly   278 GNPPAQ-LTWYRNGVAISSPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLT 341
            .||..: ..|.:.|:.|.|.:.:|.....:...||....       ||..|.:.:|.:...::  
 Frog   248 ANPEIKGYRWAKGGMIIESARDSSYETQVDYSFFTEPVS-------CEVHNEVGSTNVSTLVD-- 303

  Fly   342 VLYAPKDVYLSGANQAKVGDSVQLSCVTAPSNPQARISWSING--RPLDNST---YKTTSSSDGG 401
            |.:||:.|.........:|..|.|:|:.| .||...::|:..|  ..|.|..   .|:....|.|
 Frog   304 VQFAPRVVVEPKPTTTDMGSDVTLTCIWA-GNPPLTLTWTKKGSNMVLSNGNQLFLKSVKQEDAG 367

  Fly   402 WVSSSNISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSIL 466
                              ..||.|:...:.   ||...| .|:...||::.. .:......|...
 Frog   368 ------------------PYVCKAIVPRIG---VGEREV-TLFVNGPPIIAS-EEVQYAARGDKG 409

  Fly   467 KLQCSSAGGNPPPTLQWYKNDKIINAPS--KLVDSKITSELSLLVNASDNNAI-------YKCKV 522
            |::|......||..:.|...:.::...:  :....:.||...:|...:.||.:       |.|..
 Frog   410 KVECFIGSTPPPDRIAWAWKENVLETGTLERYTVERTTSTSGVLSTLTINNVMESDFQTRYNCTA 474

  Fly   523 QNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVP-GIRA 561
            .|:               |.|.|..|.::.:.:|| ||.|
 Frog   475 WNS---------------FGPGTAIIQLLEREVVPVGIIA 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbsNP_001286439.1 Ig 44..122 CDD:299845 32/77 (42%)
IG_like 45..137 CDD:214653 38/92 (41%)
Ig 153..231 CDD:299845 26/83 (31%)
IG_like 258..342 CDD:214653 18/84 (21%)
Ig 266..327 CDD:299845 15/61 (25%)
IG_like 357..>414 CDD:214653 14/61 (23%)
Ig 360..427 CDD:299845 17/71 (24%)
Ig <468..526 CDD:299845 12/66 (18%)
I-set 547..633 CDD:254352 6/16 (38%)
Ig 556..631 CDD:299845 5/7 (71%)
I-set 644..735 CDD:254352
IGc2 668..725 CDD:197706
IG_like 751..829 CDD:214653
IGc2 753..815 CDD:197706
Ig 852..928 CDD:143165
FN3 935..1017 CDD:238020
kirrel1XP_012808656.1 I-set 21..116 CDD:254352 40/101 (40%)
Ig 22..116 CDD:299845 39/97 (40%)
I-set 123..219 CDD:254352 34/106 (32%)
Ig 138..219 CDD:299845 30/90 (33%)
I-set 223..304 CDD:254352 19/93 (20%)
Ig_2 227..305 CDD:290606 18/90 (20%)
I-set 308..389 CDD:254352 23/103 (22%)
Ig_2 311..389 CDD:290606 22/100 (22%)
Ig5_KIRREL3 391..487 CDD:143306 20/111 (18%)
IG_like 399..487 CDD:214653 18/102 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 82 1.000 Domainoid score I8292
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D141865at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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