DRSC/TRiP Functional Genomics Resources

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Protein Alignment hbs and Kirrel2

DIOPT Version :9

Sequence 1:NP_001286439.1 Gene:hbs / 44129 FlyBaseID:FBgn0029082 Length:1235 Species:Drosophila melanogaster
Sequence 2:XP_038957463.1 Gene:Kirrel2 / 100359836 RGDID:1308456 Length:711 Species:Rattus norvegicus


Alignment Length:701 Identity:173/701 - (24%)
Similarity:266/701 - (37%) Gaps:164/701 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 PHDLQILEGTDTLLRCEVSNRAGKVQWTKDGFALGFSAVIPGFPRYSVLVDAKQNAYNLQIKNAT 109
            |.|:.:|.|.:..|.|.:....|.|||||||.|||....:||:.||.:..::....::|.||...
  Rat    38 PEDMVVLLGQEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVE 102

  Fly   110 LEDDAEYQCQVGPAAGNPAIRAN-AKL---------SIVAAPSSIVIEGYARNARVEVEERQNLT 164
            |||:|.|:||    |....:|:. |:|         .::..||..::.|...|            
  Rat   103 LEDEASYECQ----ASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGN------------ 151

  Fly   165 LHCIAE-NANPAAEIVWFQGEVPVSTAPIVTVNQTAPKRFTTSSTLHLQPRAEDDYKEFSCEARH 228
            |.|.:. :|.||.|::||:..:.:.......:........|..:||.|.|.::||.....|.||.
  Rat   152 LTCRSRGDARPAPELLWFRDGIRLDGTSFHQITLRDKATGTVENTLFLTPSSQDDGATLICRARS 216

  Fly   229 KALPPDVPMRAQVQLSVLYPPGAPFFEGYSQGETLHRGQEVQIACRSRGGNPPAQLTWYRNGVAI 293
            :|||  ......|.||:.|||....   .::.:|...|::|...|::....|.....|.:.|..:
  Rat   217 QALP--TGRDTAVTLSLQYPPMVTL---SAEPQTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPV 276

  Fly   294 SSPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAK 358
            ...:   |...|.|...|...|.    :.||..|.:.:.  .....|.|||.|       ..|||
  Rat   277 LGAR---GPRLEVVADATFLTEP----VSCEVSNAVGSA--NRSTALEVLYGP-------ILQAK 325

  Fly   359 -------VGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQS 416
                   ||.....|||.. .||..||||:..|               |..|.||..:|.:.|  
  Rat   326 PKPVSVDVGKDASFSCVWR-GNPLPRISWTRLG---------------GSQVLSSGPTLRLPS-- 372

  Fly   417 RTFIA-------VCHALNTELTQNVVGSHTVNV-LYPPSPPLLTGYNDGDILISGSILKLQCSSA 473
               :|       ||.|   |..:..||..|... |...:||::|..:.....:.|. .:|||...
  Rat   373 ---VALEDAGDYVCRA---EPRRTGVGGGTAQARLTVNAPPVVTALHPAPAFLRGP-ARLQCVVF 430

  Fly   474 GGNPPPTLQWYKNDKIINAPSK---LVDSKITSE---------LSLL----VNASDNNAIYKCKV 522
            ....|.::.|..::..:.|.|.   ||::....|         :|:|    ...||....:.|..
  Rat   431 ASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSA 495

  Fly   523 QNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRAKLICDSSSSNPP-------AKISWWK 580
            :|           .||    ...|:|.:..::|:|.:|  |:..::|:...       ..:..|:
  Rat   496 RN-----------RLG----EGRVQIHLGRRDLLPTVR--LVAGAASAATSLFMVITGVVLCCWR 543

  Fly   581 DGIPVEGLNLANRPG-LWGGSVSTLEMYVNITQDLDGIVYTCQS-----HNEVLQ---------- 629
            .|...:..||...|| ..|.|....|.....::|...||:|..:     .||.|:          
  Rat   544 HGSLSKQKNLVRIPGSSEGSSAHGPEEETGSSEDRGPIVHTDHNDLVLEENEALETKDPTNGYYK 608

  Fly   630 -RSVHETISLDILYPPKFETPQSTTF------VGVEGAPF------HVELL 667
             |.|..::||.       |.|....|      :|:.|.|.      |::|:
  Rat   609 VRGVSVSLSLG-------EAPGGGLFLPPPSPMGLPGTPTYYDFKPHLDLV 652

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbsNP_001286439.1 Ig 44..122 CDD:299845 31/76 (41%)
IG_like 45..137 CDD:214653 35/101 (35%)
Ig 153..231 CDD:299845 18/78 (23%)
IG_like 258..342 CDD:214653 16/83 (19%)
Ig 266..327 CDD:299845 13/60 (22%)
IG_like 357..>414 CDD:214653 19/63 (30%)
Ig 360..427 CDD:299845 21/73 (29%)
Ig <468..526 CDD:299845 16/73 (22%)
I-set 547..633 CDD:254352 23/109 (21%)
Ig 556..631 CDD:299845 20/98 (20%)
I-set 644..735 CDD:254352 8/36 (22%)
IGc2 668..725 CDD:197706 173/701 (25%)
IG_like 751..829 CDD:214653
IGc2 753..815 CDD:197706
Ig 852..928 CDD:143165
FN3 935..1017 CDD:238020
Kirrel2XP_038957463.1 IG_like 38..127 CDD:214653 35/92 (38%)
Ig strand A' 40..44 CDD:409353 1/3 (33%)
Ig strand B 48..57 CDD:409353 2/8 (25%)
Ig strand C 62..66 CDD:409353 3/3 (100%)
Ig strand D 75..85 CDD:409353 4/9 (44%)
Ig strand E 88..100 CDD:409353 2/11 (18%)
Ig strand F 107..115 CDD:409353 5/11 (45%)
Ig strand G 117..127 CDD:409353 3/9 (33%)
Ig 133..231 CDD:416386 27/111 (24%)
Ig strand A 134..137 CDD:409353 0/2 (0%)
Ig strand A' 140..144 CDD:409353 2/3 (67%)
Ig strand B 151..158 CDD:409353 3/18 (17%)
Ig strand C 164..169 CDD:409353 1/4 (25%)
Ig strand C' 172..174 CDD:409353 0/1 (0%)
Ig strand D 177..184 CDD:409353 0/6 (0%)
Ig strand E 191..199 CDD:409353 3/7 (43%)
Ig strand F 208..216 CDD:409353 2/7 (29%)
Ig strand G 222..228 CDD:409353 0/5 (0%)
Ig_3 234..303 CDD:404760 16/78 (21%)
Ig strand B 252..256 CDD:409353 1/3 (33%)
Ig strand C 266..270 CDD:409353 0/3 (0%)
Ig strand E 283..286 CDD:409353 0/2 (0%)
Ig strand F 292..301 CDD:409353 2/12 (17%)
Ig strand G 309..312 CDD:409353 0/2 (0%)
Ig 326..403 CDD:416386 27/100 (27%)
Ig strand A' 327..332 CDD:409353 0/4 (0%)
Ig strand B 335..344 CDD:409353 3/8 (38%)
Ig strand C 350..354 CDD:409353 3/3 (100%)
Ig strand C' 357..359 CDD:409353 1/16 (6%)
Ig strand D 362..365 CDD:409353 1/2 (50%)
Ig strand E 366..371 CDD:409353 1/4 (25%)
Ig strand F 379..387 CDD:409353 3/10 (30%)
Ig strand G 393..403 CDD:409353 3/9 (33%)
Ig 405..509 CDD:416386 24/119 (20%)
Ig strand A 406..410 CDD:409353 2/3 (67%)
Ig strand A' 412..415 CDD:409353 0/2 (0%)
Ig strand B 423..430 CDD:409353 3/6 (50%)
Ig strand C 437..442 CDD:409353 1/4 (25%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 455..462 CDD:409353 2/6 (33%)
Ig strand E 472..479 CDD:409353 2/6 (33%)
Ig strand F 490..497 CDD:409353 1/6 (17%)
Ig strand G 500..507 CDD:409353 2/10 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D141865at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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