DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mab-21 and Mab21l4

DIOPT Version :9

Sequence 1:	NP_651971.2	Gene:	mab-21 / 44127	FlyBaseID:	FBgn0029003	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001153412.1	Gene:	Mab21l4 / 71874	MGIID:	1919124	Length:	452	Species:	Mus musculus

Alignment Length:	401	Identity:	88/401 - (21%)
Similarity:	149/401 - (37%)	Gaps:	112/401 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRFISSLNDYNGRFEGLEVI-----SPTEFEIIIY 85
            :|.|::...:..|....|:..||:.|...:.|||.   ||:...|..:..     .|.:.|:::.
Mouse    30 IQSRESPRVQDYQRAENILLTVLERVHALDSRFIV---DYSRDLEAFQFALRSSEDPLDVEVLLG 91

  Fly    86 LNQMGVLNFVDDGTLPG-----C--AVLKLSDGRKRSMSLWVEFITAS------GYLSARKIRSR 137
            ::...:|....:.|.||     |  .|||.:.|.:..|:..:..:::.      |:|...|:...
Mouse    92 VDSEALLIEESEATEPGDGPAICRLGVLKEASGLEPWMTADIFSVSSEDRDKCCGHLVPSKVLCV 156

  Fly   138 FQTLVAQACDKCAYRDIVK----MIADTTEVKLR-----------IRERIIVQI-----TPAFKC 182
            .:.|:..|...|.:..::.    ..|:..|.::|           ||..::..:     .||.:.
Mouse   157 LKDLLVAAIVHCKHHRLIPPGSLNAANLKEGQMRLSLLVSSGWRKIRFNVVPVVRKKHRVPALEG 221

  Fly   183 A-------------------GLWPRSASHWPLPGIPWPHPNIVAEVKTEGFDMLSKECIALQGKN 228
            |                   .|.|.:|.||.:               :.|: :||:...|| |..
Mouse   222 AQLKLGFPEGILRRIASHGVDLVPANAQHWRI---------------STGY-LLSRLLDAL-GSL 269

  Fly   229 SAMEGDAWVLSFTDAEN-RLLQGASRRRCLSILKTLRDRHLDLPGNPVTSYHLKTLLLYECEKHP 292
            .....|:  ||..|..| ...||.|:...|                  |..||||:||:.....|
Mouse   270 PGHRLDS--LSILDRVNLESWQGGSQNHGL------------------TFDHLKTVLLWASTLFP 314

  Fly   293 REMEWEENCIADRINGIFLQLI---SCLQCRRCPHYFLPNMDLFK--GKSPGAL----ENAAKQV 348
            ...:|     ||....::.||:   .||..|:.||:..|..:|.:  |...||:    |:.|.|.
Mouse   315 APEDW-----ADLQGSVYRQLVVLLCCLATRKLPHFLYPEHNLLQDGGLDLGAIYQRVEHFASQP 374

  Fly   349 WRLTRIMLTNV 359
            ....||.:|::
Mouse   375 EESLRIHVTHL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mab-21	NP_651971.2	Mab-21	68..350	CDD:397398	73/348 (21%)
Mab21l4	NP_001153412.1	Mab-21	<146..369	CDD:281298	57/264 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10656
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010