DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mab-21 and Mab21l4

DIOPT Version :9

Sequence 1:	NP_651971.2	Gene:	mab-21 / 44127	FlyBaseID:	FBgn0029003	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001102781.1	Gene:	Mab21l4 / 501185	RGDID:	1563692	Length:	452	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	79/383 - (20%)
Similarity:	140/383 - (36%)	Gaps:	76/383 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRFISSLNDYNGRFEGLEVI-----SPTEFEIIIY 85
            :|.|::...:..|....|:..||:.....:.|||.   ||:...|..:..     .|.:.|:::.
  Rat    30 IQSRESPRVQDYQRAENILLTVLERAHALDSRFIV---DYSRDLEAFQFALRSSEDPLDVEVLLG 91

  Fly    86 LNQMGVLNFVDDGTLPG-----C--AVLKLSDGRKRSMSLWV----------EFITASGYLSARK 133
            ::...:|....:.:.||     |  .|||.:.|    :..|:          :....||::...|
  Rat    92 VDSEALLIEESEASEPGDGPAICRLGVLKEASG----LGPWMTDDIFSVSSEDRDKCSGHIIPGK 152

  Fly   134 IRSRFQTLVAQACDKCAYRDIV--------KMIADTTEVKLRIR---ERIIVQITPAFKCAGLWP 187
            :....:.|:..|...|.:..::        .:......:.|::.   .:|...:.|..|.....|
  Rat   153 VLCVLKDLLVAAIVHCKHHRLIPPGSLNAASLKGGQMRLSLQVSSGWRKIRFNVVPVVKKKHRVP 217

  Fly   188 RSASHWPLPGIPWPHPNIVAEVKTEGFDMLSKECIALQGKNSAMEGDAWVLSFTDAENRLLQG-- 250
              |....|..:.:|. .|:..:.:.|.|::            ......|.:|.....:|||..
  Rat   218 --ALEGALLKLGFPE-GILRRIASHGVDLV------------PANAQHWRISTGYLLSRLLDALG 267

  Fly   251 ---ASRRRCLSILK--TLRDRHLDLPGNPVTSYHLKTLLLYECEKHPREMEWEENCIADRINGIF 310
               ..|...||||.  .|.........:.:|..||||:||:.....|...:|     ||....::
  Rat   268 SLPGHRLDSLSILDRVNLESWRGGSQNHGLTFDHLKTVLLWASTLFPAPEDW-----ADLQGSVY 327

  Fly   311 LQLI---SCLQCRRCPHYFLPNMDLFK--GKSPGAL----ENAAKQVWRLTRIMLTNV 359
            .||:   .||..|..||:..|..:|.:  |...|.:    |:.|.|.....||.:|::
  Rat   328 RQLVVLLCCLATRNLPHFLYPECNLLQDSGLDLGIIYQQVEHFASQPEESLRIHVTHL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mab-21	NP_651971.2	Mab-21	68..350	CDD:397398	65/330 (20%)
Mab21l4	NP_001102781.1	Mab-21	144..369	CDD:281298	50/244 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10656
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010