DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mab-21 and Mab21l3

DIOPT Version :9

Sequence 1:	NP_651971.2	Gene:	mab-21 / 44127	FlyBaseID:	FBgn0029003	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001099926.1	Gene:	Mab21l3 / 295326	RGDID:	1308694	Length:	429	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	94/367 - (25%)
Similarity:	167/367 - (45%)	Gaps:	75/367 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RVQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRF--ISSLNDYNGRFEGLEVISPTEFEIIIYLN 87
            ::.:|:.||.:.::||.:||..:..|:...:.||  :.:.:.||   :.::|::|:.|.:.:.|.
  Rat    83 KMDLRQQQISQTVEEVQKIVHLLTTEISHHDSRFEAVPASDTYN---DSIKVLAPSLFHVTVPLR 144

  Fly    88 QM----GVLN-----FVDDGTLPGCAVLKLSDGRKRSMSLWVEF--------------ITASGYL 129
            .:    ||..     :...||...|. |:..:|    :..|:|.              :...|.:
  Rat   145 GLAGYKGVRTPRWRYYSLQGTKLSCP-LRDPEG----LQQWLETETFMKTLWQWHKVDVNIEGDI 204

  Fly   130 SARKIRSRFQTLVAQACDKCAYRDIVKMIADTTEVKLRIRE---RIIVQITPAFKCAGLWPRSAS 191
            ...|:...||.||..|...|.....|.::...|.|.:.:..   ::.:::.|..:....||..|
  Rat   205 VPAKVLQIFQMLVENAVRTCHLSGKVTVLEKRTTVWVAVETSTGQVELELAPTVEIPTTWPEKA- 268

  Fly   192 HWPLPGIPWPHPNIVAEVKTEGFDMLSKECIALQGKNSAMEGDAWVLSFTDAENRLLQ-----GA 251
            .||.....||.|..|..:|:.||:::::...            .|.|||:.||..|.:     |.
  Rat   269 QWPRCLKRWPSPERVECIKSFGFNLVAQSTY------------HWQLSFSQAERVLCEQLDEDGG 321

  Fly   252 SRRRCLSILKTLRDRHLDL--PG-NPV-TSYHLKTLLLYECEKHPREMEWEENCIADRINGIFLQ 312
            .||||..:|:.|::   |:  || .|| |::||:|:|.:.|||:|...:|:.      .:..||:
  Rat   322 CRRRCFQVLRQLKE---DVWCPGRRPVITTHHLQTVLFWTCEKYPHLKDWQV------FHQAFLR 377

  Fly   313 LISCLQCRRC------PHYFLPNMDLFKGKSPGALENAAKQV 348
            |:..|  .||      .|||:|..:||:..:|..|:..|::|
  Rat   378 LVRKL--HRCVSQHFLKHYFVPKSNLFQSANPSELDAVAQKV 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mab-21	NP_651971.2	Mab-21	68..350	CDD:397398	82/322 (25%)
Mab21l3	NP_001099926.1	Mab-21	125..418	CDD:281298	84/325 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3963
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10656
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910