Protein Alignment mab-21 and MAB21L2

DIOPT Version :9

• Sequence 1: NP_651971.2
• Gene: mab-21 / 44127
• FlyBaseID: FBgn0029003
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_006430.1
• Gene: MAB21L2 / 10586
• HGNCID: 6758
• Length: 359
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 271/359 - (75%)
• Similarity: 316/359 - (88%)
• Gaps: 0/359 - (0%)

  Fly     7 MIAAQSKMVYQMNKYCADRVQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRFISSLNDYNGRFEG 71
            |||||:|:|||:|||..:|.|.|||.|.|.|:|||::|.|||||||||||||||||::.:.|:||
Human     1 MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEG 65

  Fly    72 LEVISPTEFEIIIYLNQMGVLNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRS 136
            ||||||||||:::|||||||.||||||:|||||||||||||||||||||||||||||||||||||
Human    66 LEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRS 130

  Fly   137 RFQTLVAQACDKCAYRDIVKMIADTTEVKLRIRERIIVQITPAFKCAGLWPRSASHWPLPGIPWP 201
            |||||||||.|||:|||:|||||||:|||||||||.:|||||||||.|:|||||:.||:|.||||
Human   131 RFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWP 195

  Fly   202 HPNIVAEVKTEGFDMLSKECIALQGKNSAMEGDAWVLSFTDAENRLLQGASRRRCLSILKTLRDR 266
            .||.|||||.|||::|||||.:|.||.|:.|.|||||.|.:||||||.|..|.:|||:|||||||
Human   196 GPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDR 260

  Fly   267 HLDLPGNPVTSYHLKTLLLYECEKHPREMEWEENCIADRINGIFLQLISCLQCRRCPHYFLPNMD 331
            ||:|||.|:.:||:||||||||||||||.:|:|:|:.||:|||.|||||||||||||||||||:|
Human   261 HLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLD 325

  Fly   332 LFKGKSPGALENAAKQVWRLTRIMLTNVRCLEEL 365
            ||:||...|||:||||.|||.|.:|||.:.|::|
Human   326 LFQGKPHSALESAAKQTWRLAREILTNPKSLDKL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mab-21	NP_651971.2	Mab-21	68..350	CDD:397398	221/281 (79%)
MAB21L2	NP_006430.1	Mab-21	62..344	CDD:397398	221/281 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157238
Domainoid	1	1.000	483	1.000	Domainoid score	I404
eggNOG	1	0.900	-	-		E1_KOG3963
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	580	1.000	Inparanoid score	I1025
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48626
OrthoDB	1	1.010	-	-		D336176at33208
OrthoFinder	1	1.000	-	-		FOG0002743
OrthoInspector	1	1.000	-	-		mtm8572
orthoMCL	1	0.900	-	-		OOG6_105865
Panther	1	1.100	-	-	O	PTHR10656
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2624
SonicParanoid	1	1.000	-	-		X1828
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800