Protein Alignment AstA-R1 and KISS1R

DIOPT Version :9

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_115940.2
• Gene: KISS1R / 84634
• HGNCID: 4510
• Length: 398
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 126/376 - (33%)
• Similarity: 181/376 - (48%)
• Gaps: 52/376 - (13%)

  Fly    13 TLISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVST-I 76
            |:.:|.|.|||||..|.|......:                 ||:|.      .|...|.|.. :
Human     3 TVATSGPNASWGAPANASGCPGCGA-----------------NASDG------PVPSPRAVDAWL 44

  Fly    77 VPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWP 141
            ||:||..:...||:||.|||.|:..::.||:.||..|.|||.:|:.|::.||||||..|.||.|.
Human    45 VPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWV 109

  Fly   142 FGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTA 206
            .|:..||||.|:..|:...:..||..||.||:...|.|:.::..||.|.|....:..|:.....:
Human   110 LGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVS 174

  Fly   207 IPVALSHSV----RIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLA 267
            .||...|.:    |.|     ...|......|..::|..     .|:.|:.||...|..|..||.
Human   175 APVLALHRLSPGPRAY-----CSEAFPSRALERAFALYN-----LLALYLLPLLATCACYAAMLR 229

  Fly   268 RLWKSAPGCKPSAESRKG----------KRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGG- 321
            .|.:.|....|:..:.:|          :.:|:|:|..|||.||.||.||.:.|||:||...|.
Human   230 HLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSW 294

  Fly   322 ---SHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPP 369
               |:.:..::..:|.::|:||.:||:|||||..:||:|||:|..|....|
Human   295 HPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRP 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	55/160 (34%)
		7tm_1	91..347	CDD:278431	91/273 (33%)
KISS1R	NP_115940.2	7tm_4	53..>157	CDD:304433	45/103 (44%)
		7tm_1	59..323	CDD:278431	91/273 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..363		1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9822
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3950
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.950