DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and Cxcr3

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_445867.1	Gene:	Cxcr3 / 84475	RGDID:	621528	Length:	367	Species:	Rattus norvegicus

Alignment Length:	343	Identity:	100/343 - (29%)
Similarity:	174/343 - (50%)	Gaps:	56/343 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 NNYAFTSEH-TDHSDHNANDSMEYDAE------SVALERIVSTIVPVFFGIIGFAGLLGNGLVIL 97
            ::.||..|: |...|:..|:|...|:.      |:..:|   |.:||.:.::...||||||.|..
  Rat    14 SDIAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDR---TFLPVLYSLLFLLGLLGNGAVAA 75

  Fly    98 VVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSV 162
            |:::.:...|:|:..:::|||:|:|.|: .:|..|.| ...:|.||:..||....:..:..:...
  Rat    76 VLLSQRTALSSTDTFLLHLAVADVLLVL-TLPLWAVD-AAAQWVFGSGLCKVAGALFNINFYAGA 138

  Fly   163 YTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMC--AWITIVTTAIP----VALSHSVRIYQYH 221
            :.|..:||||:|::||  .:...|.:....:|:.|  .|...|..|:|    ::.||..|:
  Rat   139 FLLACISFDRYLSIVH--ATQIYRRDPWVRVALTCIVVWGLCVLFALPDFIFLSASHDQRL---- 197

  Fly   222 GNAGTACVFSTEEEIWSLVG---FQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESR 283
             || |.|.::..:     ||   .:|...::.::.||.::.:.|..:||.|..|
  Rat   198 -NA-THCQYNFPQ-----VGRTALRVLQLVAGFLMPLLVMAYCYAHILAVLLVS----------- 244

  Fly   284 KGKR--RVTRMVVVVVLAFAICWLPIHVILVLKAL--------NLYGGSHLSVIIQIISHVVAYT 338
            :|:|  |..|:|||||:|||:||.|.|:::::..|        |....||:.|...:.|. :.|.
  Rat   245 RGQRRFRAMRLVVVVVVAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKSVTSG-MGYM 308

  Fly   339 NSCINPILYAFLSDNFRK 356
            :.|:||:||||:...|::
  Rat   309 HCCLNPLLYAFVGVKFKE 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	46/162 (28%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	79/274 (29%)
Cxcr3	NP_445867.1	7tm_1	73..317	CDD:278431	76/270 (28%)
Cxcr3	NP_445867.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000