Protein Alignment AstA-R1 and npy2rl

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001314731.1
• Gene: npy2rl / 795311
• ZFINID: ZDB-GENE-111115-4
• Length: 373
• Species: Danio rerio
• Alignment Length: 389
• Identity: 116/389 - (29%)
• Similarity: 172/389 - (44%)
• Gaps: 75/389 - (19%)

  Fly    30 SIISVSNSSGNNYAFTSEHTDHSDHNAN-------DSMEYDAESVALERIVSTIVPVFFGIIGFA 87
            |:..::.|||:......|  |.||...|       ||.:.....|.|....|||:        ..
Zfish     3 SLSLINGSSGSKDLSIGE--DSSDLTLNHPLLELGDSTKLLGVQVVLILAYSTII--------LL 57

  Fly    88 GLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQY 152
            |::||.|||.||...:.:|:.||..|.||||:|:|....|:|||....:|.||.||.|.|..:.|
Zfish    58 GVVGNSLVIYVVYKFKTLRTVTNFFIANLAVADLLVNTLCLPFTLAYTLLREWKFGQVLCFTLPY 122

  Fly   153 MIVVTCHCSVYTLVLMSFDRFLAVV-HPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVR 216
            ...:..|.|..||.:::.||...:| |..|.||..|   ..|.|...|:.....|.|:|
Zfish   123 AQGLAVHVSTITLNVIALDRHRCIVYHLDTRMSKDT---CFLVIAITWVVSAVLASPLA------ 178

  Fly   217 IYQYHG-------NAGTAC-----VFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARL 269
            |::.:|       |:...|     ..||:..::|     :|..|..||.||.:|.|.|:    |:
Zfish   179 IFREYGIVDLSPDNSIEVCGEKWPDSSTDSTLYS-----ISTLLLQYVLPLAIISFAYI----RI 234

  Fly   270 WKS-----APGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHV----------ILVLKALNLY 319
            |..     :|..:.....|  :|:.|:|:|.:|:.||:.|||.|.          :|.:|...|
Zfish   235 WSKLRNHVSPVGRNDRHHR--RRKTTKMLVTMVVVFAVSWLPFHAFQLAIDIDHSVLDMKDFRL- 296

  Fly   320 GGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSP-PPLMTNQQVTKTTRT 382
                    :..:.|:||..::..||:||.:::.|:|.||..|..|... ..|.|..|...|.|:
Zfish   297 --------LYTVFHIVAMCSTFANPLLYGWMNRNYRSAFVAVFRCKERLDSLHTEGQPAATVRS 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	93/310 (30%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	13/25 (52%)
		TM helix 3	147..177	CDD:320224	8/29 (28%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	9/28 (32%)
		TM helix 6	284..314	CDD:320224	12/39 (31%)
		TM helix 7	326..351	CDD:320224	7/24 (29%)
npy2rl	NP_001314731.1	7tm_GPCRs	45..327	CDD:475119	96/318 (30%)
		TM helix 1	47..71	CDD:410628	12/31 (39%)
		TM helix 2	80..102	CDD:410628	11/21 (52%)
		TM helix 3	118..140	CDD:410628	5/21 (24%)
		TM helix 4	161..177	CDD:410628	4/15 (27%)
		TM helix 5	209..232	CDD:410628	9/27 (33%)
		TM helix 6	258..280	CDD:410628	10/21 (48%)
		TM helix 7	295..320	CDD:410628	8/33 (24%)