DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstA-R1 and Kiss1r

DIOPT Version :9

Sequence 1:NP_524700.1 Gene:AstA-R1 / 44126 FlyBaseID:FBgn0266429 Length:394 Species:Drosophila melanogaster
Sequence 2:NP_076482.2 Gene:Kiss1r / 78976 RGDID:70930 Length:396 Species:Rattus norvegicus


Alignment Length:368 Identity:117/368 - (31%)
Similarity:178/368 - (48%) Gaps:56/368 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 PKASWGATGN-----GSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIVP 78
            |..||.|..|     |..::.|:..|:                           |...:.:.:||
  Rat     9 PNVSWWAPSNASGCPGCGVNASDGPGS---------------------------APRPLDAWLVP 46

  Fly    79 VFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFG 143
            :||..:...||:||.|||.|:..::.|::.||..|.|||.:|:.|::.||||||..|.||.|..|
  Rat    47 LFFAALMLLGLVGNSLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVLG 111

  Fly   144 NVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIP 208
            :..||||.|:..|:...:..||..||.||:...|.|:.::..||.|.|....:..|:.....:.|
  Rat   112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSAP 176

  Fly   209 VALSH--SVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWK 271
            |...|  |...:.|...|..:........:::|        |:.|:.||...|..|..||..|.:
  Rat   177 VLALHRLSPGPHTYCSEAFPSRALERAFALYNL--------LALYLLPLLATCACYGAMLRHLGR 233

  Fly   272 SAPGCKPSAESRKG----------KRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGG----S 322
            :|....|:..:.:|          :.:|:|:|..|||.||.||.||.:.|||:||...|.    |
  Rat   234 AAVRPAPTDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRS 298

  Fly   323 HLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCG 365
            :.:..::|.:|.::|:||.:||:|||||..:||:||.:|..||
  Rat   299 YAAYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCG 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R1NP_524700.1 7tm_4 83..>240 CDD:304433 53/158 (34%)
7tm_1 91..347 CDD:278431 90/271 (33%)
Kiss1rNP_076482.2 7tmA_KiSS1R 43..334 CDD:320223 103/298 (35%)
TM helix 1 45..69 CDD:320223 12/23 (52%)
TM helix 2 78..100 CDD:320223 11/21 (52%)
TM helix 3 116..138 CDD:320223 8/21 (38%)
TM helix 4 161..177 CDD:320223 1/15 (7%)
TM helix 5 202..225 CDD:320223 6/30 (20%)
TM helix 6 262..284 CDD:320223 11/21 (52%)
TM helix 7 302..327 CDD:320223 11/24 (46%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 346..396
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1294084at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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