Protein Alignment AstA-R1 and SSTR5

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001044.1
• Gene: SSTR5 / 6755
• HGNCID: 11334
• Length: 364
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 131/397 - (32%)
• Similarity: 198/397 - (49%)
• Gaps: 76/397 - (19%)

  Fly    17 SW----PKASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIV 77
            ||    |.|:.|...|.:::..:.|:|                        |.:|        :|
Human    11 SWNASSPGAASGGGDNRTLVGPAPSAG------------------------ARAV--------LV 43

  Fly    78 PVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPF 142
            ||.:.::..|||.||.|||.||:...:|::.||:.|:||||:|:|::: .:||.||......|||
Human    44 PVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYML-GLPFLATQNAASFWPF 107

  Fly   143 GNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAI 207
            |.|.|:.|..:..|....||:.|.:||.||:||||||::|...|..|.|.||...||:..:..::
Human   108 GPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSL 172

  Fly   208 PVALSHSVRIYQYHGNAGTACVFSTEEEI--WSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLW 270
            |:.:...|:       .|..|..|..|.:  |..| |.:...:..:.|||.:||..|:.::.::
Human   173 PLLVFADVQ-------EGGTCNASWPEPVGLWGAV-FIIYTAVLGFFAPLLVICLCYLLIVVKV- 228

  Fly   271 KSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLP------IHVILVLKALNLYGGSHLSVIIQ 329
             .|.|.:.....|:.:|:|||||:||||.||.||||      :::.:.|.......|.:..|:|
Human   229 -RAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVI- 291

  Fly   330 IISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWC---GS-----------PPPLMTNQQVTKTT 380
                 ::|.|||.||:||.|||||||::|:||: |   ||           |..:...|:.|...
Human   292 -----LSYANSCANPVLYGFLSDNFRQSFQKVL-CLRKGSGAKDADATEPRPDRIRQQQEATPPA 350

  Fly   381 RTATGNG 387
            ..|..||
Human   351 HRAAANG 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	109/290 (38%)
		TM helix 1	76..102	CDD:320224	13/25 (52%)
		TM helix 2	109..135	CDD:320224	13/25 (52%)
		TM helix 3	147..177	CDD:320224	12/29 (41%)
		TM helix 4	189..209	CDD:320224	6/19 (32%)
		TM helix 5	239..268	CDD:320224	8/28 (29%)
		TM helix 6	284..314	CDD:320224	16/35 (46%)
		TM helix 7	326..351	CDD:320224	11/24 (46%)
SSTR5	NP_001044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		3/8 (38%)
		7tmA_SSTR5	51..315	CDD:320640	106/280 (38%)
		TM helix 2	75..101	CDD:320640	13/26 (50%)
		TM helix 3	112..142	CDD:320640	12/29 (41%)
		TM helix 4	154..176	CDD:320640	7/21 (33%)
		TM helix 5	198..227	CDD:320640	8/29 (28%)
		TM helix 6	241..271	CDD:320640	16/29 (55%)
		TM helix 7	283..308	CDD:320640	12/30 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..364		6/31 (19%)