Protein Alignment AstA-R1 and SSTR3

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001042.1
• Gene: SSTR3 / 6753
• HGNCID: 11332
• Length: 418
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 108/341 - (31%)
• Similarity: 165/341 - (48%)
• Gaps: 42/341 - (12%)

  Fly    45 TSEHTDHSDHNANDSMEYDA--------ESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVA 101
            :|..|.....||:.:...||        .|.|...:...::|:.:.::...|||||.|||.||:.
Human     7 SSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLR 71

  Fly   102 NQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLV 166
            :....|.||:.|:|||::|.||:: .:||.|....|..||||::.|:.|..:..:....|::.|.
Human    72 HTASPSVTNVYILNLALADELFML-GLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLT 135

  Fly   167 LMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFS 231
            :||.||:||||||..|...||...|.......|:......:||.:...|      ....:.|...
Human   136 VMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV------PRGMSTCHMQ 194

  Fly   232 TEE--EIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLA-------RLWKSAPGCKPSAESRKGKR 287
            ..|  ..|. .||.:......:..||.:||..|:.::.       |:|  ||.|:   ..|:.:|
Human   195 WPEPAAAWR-AGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVW--APSCQ---RRRRSER 253

  Fly   288 RVTRMVVVVVLAFAICWLPIHVILVLKAL------NLYGGSHLSVIIQIISHVVAYTNSCINPIL 346
            |||||||.||..|.:||:|.:|:.::..:      ..:.|.:..|:      .:.|.|||.||||
Human   254 RVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVV------ALPYANSCANPIL 312

  Fly   347 YAFLSDNFRKAFRKVV 362
            |.|||..|::.||:|:
Human   313 YGFLSYRFKQGFRRVL 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	97/297 (33%)
		TM helix 1	76..102	CDD:320224	11/25 (44%)
		TM helix 2	109..135	CDD:320224	12/25 (48%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	2/19 (11%)
		TM helix 5	239..268	CDD:320224	7/35 (20%)
		TM helix 6	284..314	CDD:320224	15/29 (52%)
		TM helix 7	326..351	CDD:320224	11/24 (46%)
SSTR3	NP_001042.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		4/13 (31%)
		7tm_GPCRs	45..324	CDD:475119	97/297 (33%)
		TM helix 1	47..71	CDD:410628	11/23 (48%)
		TM helix 2	80..101	CDD:410628	10/21 (48%)
		TM helix 3	117..139	CDD:410628	4/21 (19%)
		TM helix 4	162..178	CDD:410628	1/15 (7%)
		TM helix 5	204..227	CDD:410628	6/22 (27%)
		TM helix 6	256..278	CDD:410628	12/21 (57%)
		TM helix 7	292..317	CDD:410628	12/30 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..418