Protein Alignment AstA-R1 and oprm1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_571782.2
• Gene: oprm1 / 65088
• ZFINID: ZDB-GENE-010125-1
• Length: 382
• Species: Danio rerio
• Alignment Length: 376
• Identity: 127/376 - (33%)
• Similarity: 200/376 - (53%)
• Gaps: 20/376 - (5%)

  Fly    26 TGNGS--IISVSNSSGNNYAFTSEHTDHSDH--NANDSM-----EYDAESVALERIVSTIVPVFF 81
            |||.|  :.::||...:|.:....:..:|..  |.|.|:     |.|..|..:  ||:.|:...:
Zfish     5 TGNISDLLYALSNPMVSNSSIFCRNFSNSSGLVNMNSSVCDRTPELDKSSTPV--IVAIIITALY 67

  Fly    82 GIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVW 146
            .|:...||:||.||:.|::...:|::.||:.|.|||::|.| ....:||.:.:|::..||||:..
Zfish    68 SIVCVMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSL-ATSTLPFQSVNYLMGTWPFGDEL 131

  Fly   147 CKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVAL 211
            ||.|..:.......|::||..||.||::||.|||.::..||.|||.:..:|.||......:||.:
Zfish   132 CKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMV 196

  Fly   212 SHSVRIYQYHGNAGTAC--VFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAP 274
            ..|. ....|.|....|  :|......|..: .::..|:.:::.|:.:|...|..|:.|| ||..
Zfish   197 MAST-TSDLHSNGIIDCTLLFPHPSWYWENL-LKICVFIFAFIMPVLIITVCYGLMILRL-KSVR 258

  Fly   275 GCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQIISHVVAYTN 339
            ....|.|..:..||:||||:|||..|.:||.|||:.:::|||.....|.|..|.......:.|||
Zfish   259 MLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTIPNSLLQTITWHFCIALGYTN 323

  Fly   340 SCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTNQQVTKTTRTATGNGTSN 390
            ||:||:|||||.:||::.||:  :|...|.::..|..|: :|....:|.|:
Zfish   324 SCLNPVLYAFLDENFKRCFRE--FCVPSPSVLDLQNSTR-SRNPQRDGQSS 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	102/284 (36%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	11/29 (38%)
		TM helix 4	189..209	CDD:320224	6/19 (32%)
		TM helix 5	239..268	CDD:320224	5/28 (18%)
		TM helix 6	284..314	CDD:320224	15/29 (52%)
		TM helix 7	326..351	CDD:320224	12/24 (50%)
oprm1	NP_571782.2	7tmA_Mu_opioid_R	61..342	CDD:320218	102/284 (36%)
		TM helix 1	62..88	CDD:320218	9/25 (36%)
		TM helix 2	95..121	CDD:320218	10/26 (38%)
		TM helix 3	132..162	CDD:320218	11/29 (38%)
		TM helix 4	174..196	CDD:320218	8/21 (38%)
		TM helix 5	224..253	CDD:320218	5/29 (17%)
		TM helix 6	268..298	CDD:320218	15/29 (52%)
		TM helix 7	310..335	CDD:320218	12/24 (50%)