Protein Alignment AstA-R1 and BDKRB1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_000701.2
• Gene: BDKRB1 / 623
• HGNCID: 1029
• Length: 353
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 93/364 - (25%)
• Similarity: 161/364 - (44%)
• Gaps: 54/364 - (14%)

  Fly    14 LISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIVP 78
            :.||||...            ..||..:..|....|  :..||.::.:          ::..::|
Human     1 MASSWPPLE------------LQSSNQSQLFPQNAT--ACDNAPEAWD----------LLHRVLP 41

  Fly    79 VFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATD-YVLPEWPF 142
            .|...|.|.|||||..|:||.:..::..:...:.:.|||.||::||: .:||.|.: :....|||
Human    42 TFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVL-GLPFWAENIWNQFNWPF 105

  Fly   143 GNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAI 207
            |.:.|:.:..:|......|::.:|.:|.||:..:|||:.|...:..|.|.:..:..|:.....:|
Human   106 GALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSI 170

  Fly   208 PVALSHSVR------IYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGML 266
            |..|..|::      |        |||:.....|.|..... |...:..::.||..|.|....:|
Human   171 PTFLLRSIQAVPDLNI--------TACILLLPHEAWHFARI-VELNILGFLLPLAAIVFFNYHIL 226

  Fly   267 ARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKAL-------NLYGGSHL 324
            |.|.......:.....||.. :.|.:::.:|:||.:||.|.|....|:.|       ..:....:
Human   227 ASLRTREEVSRTRCGGRKDS-KTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFI 290

  Fly   325 SVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVW 363
            .:.:| :::..|:|||.:||::|.|:.    :.||..||
Human   291 DLGLQ-LANFFAFTNSSLNPVIYVFVG----RLFRTKVW 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	79/296 (27%)
		TM helix 1	76..102	CDD:320224	12/25 (48%)
		TM helix 2	109..135	CDD:320224	10/26 (38%)
		TM helix 3	147..177	CDD:320224	7/29 (24%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	6/28 (21%)
		TM helix 6	284..314	CDD:320224	9/29 (31%)
		TM helix 7	326..351	CDD:320224	9/24 (38%)
BDKRB1	NP_000701.2	7tmA_BK-1	38..323	CDD:320502	81/300 (27%)
		TM helix 1	39..65	CDD:320502	12/25 (48%)
		TM helix 2	72..97	CDD:320502	10/25 (40%)
		TM helix 3	110..140	CDD:320502	7/29 (24%)
		TM helix 4	153..174	CDD:320502	4/20 (20%)
		TM helix 5	199..228	CDD:320502	6/29 (21%)
		TM helix 6	243..273	CDD:320502	10/30 (33%)
		TM helix 7	291..316	CDD:320502	9/25 (36%)