Protein Alignment AstA-R1 and ACKR3

DIOPT Version :9

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_064707.1
• Gene: ACKR3 / 57007
• HGNCID: 23692
• Length: 362
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 86/350 - (24%)
• Similarity: 160/350 - (45%)
• Gaps: 65/350 - (18%)

  Fly    46 SEHTDHSD----HNANDSMEYDA--------ESVALERIVSTIVPVFFGIIGFAGLLGNGLVILV 98
            ||..:.||    .|::|.:..|.        :||.|..:  :.:.:|..:|   |::.|.:|:.|
Human     9 SEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTL--SFIYIFIFVI---GMIANSVVVWV 68

  Fly    99 VVANQQMRST---TNLLIINLAVSDILFVIFCVPFTATDYVL-PEWPFGNVWCKFVQYMIVVTCH 159
               |.|.::|   |:..|:|||::| |:|:..:|......|. .:||.|.:.||....:..:...
Human    69 ---NIQAKTTGYDTHCYILNLAIAD-LWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF 129

  Fly   160 CSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNA 224
            .|::.|..||.||:|::.:...:.|.|.:....:..:..|:.....::|.  ::.::......|.
Human   130 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPD--TYYLKTVTSASNN 192

  Fly   225 GTAC-VFSTEEEI--WSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGK 286
            .|.| .|..|..|  | |:|.::...:..:..|.::|...|. :|||        ..||.|.:.|
Human   193 ETYCRSFYPEHSIKEW-LIGMELVSVVLGFAVPFSIIAVFYF-LLAR--------AISASSDQEK 247

  Fly   287 RRVTRMVVVVVLAFAICWLPIHVILVLKALN--------------LYGGSHLSVIIQIISHVVAY 337
            ....:::...|:.|.:||||.||.::|...:              |:...|::..:.::
Human   248 HSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLV------ 306

  Fly   338 TNSCINPILYAFLSDNFR----KAF 358
             :.|:||:||:|::.|:|    |||
Human   307 -HCCVNPVLYSFINRNYRYELMKAF 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	41/163 (25%)
		7tm_1	91..347	CDD:278431	65/276 (24%)
ACKR3	NP_064707.1	7tm_1	62..315	CDD:278431	65/275 (24%)
		C-terminal cytoplasmic tail	324..362		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147280
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840