DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and galr1a

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_696215.1	Gene:	galr1a / 567820	ZFINID:	ZDB-GENE-060503-290	Length:	347	Species:	Danio rerio

Alignment Length:	360	Identity:	116/360 - (32%)
Similarity:	193/360 - (53%)	Gaps:	34/360 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 TSEHTDHSDHNANDSMEYDAES---VALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQ--Q 104
            |..::|.....:|..:|...::   :..:.:|:.::   ||:|...|:|||.|||.|:...:  |
Zfish     3 TQNNSDLDRPRSNIDLEAPEKNLFGIGTDNLVTLLI---FGLIFTLGVLGNSLVITVLAQRKPGQ 64

  Fly   105 MRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMS 169
            .|||||:.|:||:|:|:.:::||:||.:|.|:||.|..|...|||:.|...|:...|::||..||
Zfish    65 QRSTTNIFILNLSVADLSYLLFCIPFQSTVYMLPTWILGAFICKFIHYFFTVSMLVSIFTLSAMS 129

  Fly   170 FDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEE 234
            .||::|:||...|.|:|..|:|.:.::..|:.....|.|||        .|.|      :..:|:
Zfish   130 VDRYIAIVHCRKSSSIRVARHALIGVLVIWVLSFAMATPVA--------YYQG------IVESED 180

  Fly   235 ------EIW----SLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRV 289
                  |:|    ....:.|..|:..||.||.||.|.|..:|..|.|.....  |.:|...|::.
Zfish   181 NSTFCWEVWPDHDRRKIYVVCTFVFGYVLPLILISFCYAKVLNHLHKKLRNV--SKKSEASKKKT 243

  Fly   290 TRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNF 354
            .:.|:|||:.|.:.|||.||:.:......:..:..|.::::.:|.:||:||.:||::|||||:||
Zfish   244 AQTVLVVVVVFCLSWLPHHVVHLWVEFGSFPLNQASFVLRVAAHCLAYSNSSVNPVIYAFLSENF 308

  Fly   355 RKAFRKVVWCGSPPPLMTNQQVTKTTRTATGNGTS 389
            |:|:::|..|.......||:.....::|.....|:
Zfish   309 RQAYKQVFRCQVASECPTNEAREMKSKTEAAPSTN 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	60/168 (36%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	91/267 (34%)
galr1a	XP_696215.1	7tm_1	49..301	CDD:278431	91/267 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3307
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3501
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm6485
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1132
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.970