Protein Alignment AstA-R1 and tacr1b

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001268728.1
• Gene: tacr1b / 564017
• ZFINID: ZDB-GENE-091117-17
• Length: 412
• Species: Danio rerio
• Alignment Length: 402
• Identity: 102/402 - (25%)
• Similarity: 173/402 - (43%)
• Gaps: 93/402 - (23%)

  Fly    32 ISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESV-ALERIVSTIVPVFFGIIGFAGLLGNGLV 95
            |:..|||.:|.:..|.        .||:..:..:.| .:.:||  :..:.:..|....::||..|
Zfish     6 ITSPNSSADNGSAGSP--------VNDTEVFGNQFVQPVWQIV--LWAIAYCTIVLVSVVGNITV 60

  Fly    96 ILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHC 160
            |.:::|:::||:.||..::|||.::.....|.........|..||.||.|:|:|..:..:.....
Zfish    61 IWIILAHKRMRTVTNYFLVNLAFAEASMSAFNTVINFIYAVHNEWYFGLVYCRFHNFFPIAAVFA 125

  Fly   161 SVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCA-WITIVTTAIPVALSHSVRIYQYHGNA 224
            |:|::..::.||::|::||   :..|.....|..::|. |...:..|.|          ||:.::
Zfish   126 SIYSMTAIALDRYMAIIHP---LQQRLSSAETKLVVCVIWALALMLAFP----------QYYFSS 177

  Fly   225 GTA-------CVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFL--------YMGMLARLWKS-A 273
             ||       |..:..|  :|:..||.::    ||..:.||.||        |:.:...||.| .
Zfish   178 -TAQLPGRVVCYINWPE--YSMWDFQKTY----YVCVVVLIYFLPLLVMGCAYLVVGCFLWASEI 235

  Fly   274 PGCKPS--AESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQIISHV-- 334
            ||....  .|....||:|.:|::|||..||.||||.||..              ::.|.:.|:
Zfish   236 PGDSSDRYREQLIAKRKVVKMMIVVVCTFATCWLPYHVYF--------------IVHQFLPHLFE 286

  Fly   335 -------------VAYTNSCINPILYAFLSDNFRKAFRKVV-WCGSPPP-------------LMT 372
                         :|.:::..|||:|..|:|.||..|::.. ||...|.             |.|
Zfish   287 ERYIQQVYLGIMWLAMSSTMYNPIIYCLLNDRFRAGFQQAFSWCPCVPQGSYEGLELKSTRYLQT 351

  Fly   373 NQQVTKTTRTAT 384
            ...:.:.:|..|
Zfish   352 QASIFRASRMET 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	83/316 (26%)
		TM helix 1	76..102	CDD:320224	5/25 (20%)
		TM helix 2	109..135	CDD:320224	6/25 (24%)
		TM helix 3	147..177	CDD:320224	7/29 (24%)
		TM helix 4	189..209	CDD:320224	4/20 (20%)
		TM helix 5	239..268	CDD:320224	9/36 (25%)
		TM helix 6	284..314	CDD:320224	15/29 (52%)
		TM helix 7	326..351	CDD:320224	7/39 (18%)
tacr1b	NP_001268728.1	7tm_GPCRs	40..323	CDD:475119	84/318 (26%)
		TM helix 1	42..66	CDD:410628	5/23 (22%)
		TM helix 2	75..97	CDD:410628	5/21 (24%)
		TM helix 3	113..135	CDD:410628	3/21 (14%)
		TM helix 4	156..172	CDD:410628	4/25 (16%)
		TM helix 5	201..224	CDD:410628	6/26 (23%)
		TM helix 6	254..276	CDD:410628	12/35 (34%)
		TM helix 7	291..316	CDD:410628	5/24 (21%)