Protein Alignment AstA-R1 and nmbr

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_690325.2
• Gene: nmbr / 561834
• ZFINID: ZDB-GENE-041014-369
• Length: 372
• Species: Danio rerio
• Alignment Length: 363
• Identity: 110/363 - (30%)
• Similarity: 174/363 - (47%)
• Gaps: 30/363 - (8%)

  Fly    47 EHTDHSDHNANDSMEYDAESVALER---IVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRST 108
            :||...|....::...|..|...|.   |:..::|..:.:|...|||||..::.:.:....|||.
Zfish     2 DHTFSEDTAVYENFTEDWTSDGGETVHFIIQCVIPSVYILIITVGLLGNITLVKIFITTSAMRSV 66

  Fly   109 TNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRF 173
            .|:.|.:|||.|:|.::.|||..|..|...||.||.|.||.:..:.:.:...||:||..:|.||.
Zfish    67 PNIFISSLAVGDLLLLVTCVPVDAFRYFYEEWIFGTVACKMIPVIQLTSVGVSVFTLTALSADRH 131

  Fly   174 LAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACV-FSTEEEIW 237
            .|:|:|:...|........|..:..|:..|..|||.|:...|..........|||| :....|:.
Zfish   132 KAIVNPMDIQSSSAVFWTCLKAITIWVVSVLLAIPEAVFSQVVHMPDKNTTFTACVPYPLSNEMH 196

  Fly   238 SLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSA---PG-----CKPSAESRKGKRRVTRMVV 294
            ..: ..:..||..::.||::|...|..:...|.|||   ||     .|...|:||   |:.::|:
Zfish   197 PKI-HSIMIFLVYFLIPLSIISVYYYHIARTLIKSAHDMPGEISEHSKRQTETRK---RLAKIVL 257

  Fly   295 VVVLAFAICWLPIHVILVLKALNL----YGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFR 355
            |.|..||:||.|.||:.:.::.|.    ...|||  ||.:::.|:::::||:||.....||::||
Zfish   258 VFVGLFALCWFPNHVLYMYRSFNYRQIDSSLSHL--IITLVARVLSFSSSCVNPFALYLLSESFR 320

  Fly   356 KAFRKVVWCGSPPPLMTNQQVTKTTRTATGNGTSNIEM 393
            :.|...:.|        .|:..:...|:....||.|.|
Zfish   321 RHFNNQLLC--------RQRKYQERNTSYLQSTSAIRM 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	95/295 (32%)
		TM helix 1	76..102	CDD:320224	7/25 (28%)
		TM helix 2	109..135	CDD:320224	11/25 (44%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	6/28 (21%)
		TM helix 6	284..314	CDD:320224	12/29 (41%)
		TM helix 7	326..351	CDD:320224	7/24 (29%)
nmbr	XP_690325.2	7tm_GPCRs	33..323	CDD:475119	95/295 (32%)
		TM helix 1	35..59	CDD:410628	7/23 (30%)
		TM helix 2	68..90	CDD:410628	10/21 (48%)
		TM helix 3	106..128	CDD:410628	5/21 (24%)
		TM helix 4	151..167	CDD:410628	5/15 (33%)
		TM helix 5	198..221	CDD:410628	5/23 (22%)
		TM helix 6	253..275	CDD:410628	10/21 (48%)
		TM helix 7	291..316	CDD:410628	8/26 (31%)