Protein Alignment AstA-R1 and npffr2a

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001098579.1
• Gene: npffr2a / 560955
• ZFINID: ZDB-GENE-060526-183
• Length: 422
• Species: Danio rerio
• Alignment Length: 360
• Identity: 109/360 - (30%)
• Similarity: 188/360 - (52%)
• Gaps: 59/360 - (16%)

  Fly    66 SVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPF 130
            |||...|||.:      :|....::|||:|..:|:.::.||:.|||.|:|||:||:|..|||:|.
Zfish    44 SVAAVFIVSYL------LIFLVCMIGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPT 102

  Fly   131 TATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPV-TSMSLRTERNATLA 194
            |..|.::..||||::.||....:..::...||:|||.::.|||..:|:|. ..:::.|   ||..
Zfish   103 TLLDNIITGWPFGSMVCKMSGMVQGISVSASVFTLVAIAVDRFRCIVYPFKQKLTIST---ATFI 164

  Fly   195 IMCAWITIVTTAIP------VALSHSVRIYQYHGNAGTACVFSTEE--------EIWSLVGFQVS 245
            |:..|:..|:...|      |....::|:::  ||..::..:...|        :|::.|
Zfish   165 IVIIWVLAVSIMCPSGVMLQVTKEQNIRVFR--GNNRSSPFYWCRENWPNQEMRKIYTTV----- 222

  Fly   246 FFLSSYVAPLTLICFLYMGMLARLWKSA--PGCKPSAESR----KGKRRVTRMVVVVVLAFAICW 304
            .|.:.|:|||:||..:|..:...|:|:|  .|.|...::|    |.|:||.:|:::|.|.|.:.|
Zfish   223 LFANIYLAPLSLIVIMYARIGITLFKTAMPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSW 287

  Fly   305 LPIHVILVL-----------KALNLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAF 358
            ||:..:::|           :.:|:|        |...:|.:|:.||.:|||:|.|.::|||:.|
Zfish   288 LPLWTLMMLTDYVKLTEHQYRVINIY--------IYPFAHWLAFFNSSVNPIIYGFFNENFRRGF 344

  Fly   359 RKVVWCGSPPPLMTNQQVTKTTRTATGNGTSNIEM 393
            :.:...|..|  :..|..|.:.| ..||....:.:
Zfish   345 QAIFKFGLCP--VGGQHRTYSHR-VQGNSVQPVNL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	95/314 (30%)
		TM helix 1	76..102	CDD:320224	6/25 (24%)
		TM helix 2	109..135	CDD:320224	15/25 (60%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	6/25 (24%)
		TM helix 5	239..268	CDD:320224	9/28 (32%)
		TM helix 6	284..314	CDD:320224	12/40 (30%)
		TM helix 7	326..351	CDD:320224	10/24 (42%)
npffr2a	NP_001098579.1	7tmA_NPFFR2	47..344	CDD:320646	98/320 (31%)
		TM helix 1	48..74	CDD:320646	9/31 (29%)
		TM helix 2	81..107	CDD:320646	15/25 (60%)
		TM helix 3	119..149	CDD:320646	10/29 (34%)
		TM helix 4	160..181	CDD:320646	7/23 (30%)
		TM helix 5	216..245	CDD:320646	10/33 (30%)
		TM helix 6	267..297	CDD:320646	11/29 (38%)
		TM helix 7	312..337	CDD:320646	11/32 (34%)