DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and Galr1

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_037090.2	Gene:	Galr1 / 50577	RGDID:	2656	Length:	346	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	124/327 - (37%)
Similarity:	184/327 - (56%)	Gaps:	31/327 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SDHNANDSMEYDAE-----SVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQ--QMRSTT 109
            |:.|.:|. |..||     .:.:|..::.:|   ||:|...|:|||.|||.|:..::  :.||||
  Rat     9 SEGNGSDP-EPPAEPRPLFGIGVENFITLVV---FGLIFAMGVLGNSLVITVLARSKPGKPRSTT 69

  Fly   110 NLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFL 174
            ||.|:||:::|:.:::||:||.||.|.||.|..|...|||:.|...|:...|::||..||.||::
  Rat    70 NLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYV 134

  Fly   175 AVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQ--YHGNAG-TACVFSTEEEI 236
            |:||...|.|||..|||.|.:...|      |:.:|::..|..||  :|.::. |.|     .|.
  Rat   135 AIVHSRRSSSLRVSRNALLGVGFIW------ALSIAMASPVAYYQRLFHRDSNQTFC-----WEH 188

  Fly   237 W----SLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVV 297
            |    ....:.|..|:..|:.||.||||.|..:|..|.|.....  |.:|...|::..:.|:|||
  Rat   189 WPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNM--SKKSEASKKKTAQTVLVVV 251

  Fly   298 LAFAICWLPIHVILVLKALNLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVV 362
            :.|.|.|||.|||.:......:..:..|...:|.:|.:||:||.:|||:|||||:|||||:::|.
  Rat   252 VVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVF 316

  Fly   363 WC 364
            .|
  Rat   317 KC 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	64/165 (39%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	99/264 (38%)
Galr1	NP_037090.2	7tm_1	49..301	CDD:278431	99/264 (38%)
Galr1	NP_037090.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	326..346
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	179	1.000	Domainoid score	I3436
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3578
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm9131
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1132
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.970