Protein Alignment AstA-R1 and OPRD1

DIOPT Version :9

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_000902.3
• Gene: OPRD1 / 4985
• HGNCID: 8153
• Length: 372
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 120/394 - (30%)
• Similarity: 186/394 - (47%)
• Gaps: 60/394 - (15%)

  Fly     2 AGHQSLALLLATLISSWPKA--SWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDA 64
            ||.:....|.|....::|.|  |.||..:|...:.|.||                        .|
Human     7 AGAELQPPLFANASDAYPSACPSAGANASGPPGARSASS------------------------LA 47

  Fly    65 ESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVP 129
            .::|:..:.|.:..|        |||||.||:..:|...:|::.||:.|.|||::|.| ....:|
Human    48 LAIAITALYSAVCAV--------GLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL-ATSTLP 103

  Fly   130 FTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLA 194
            |.:..|::..||||.:.||.|..:.......|::||.:||.||::||.|||.::..||...|.|.
Human   104 FQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLI 168

  Fly   195 IMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACV--FSTEEEIWSLVGFQVSFFLSSYVAPLTL 257
            .:|.|:......:|:.:....|    ..:....|:  |.:....|..| .::..||.::|.|:.:
Human   169 NICIWVLASGVGVPIMVMAVTR----PRDGAVVCMLQFPSPSWYWDTV-TKICVFLFAFVVPILI 228

  Fly   258 ICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKAL------ 316
            |...|..||.|| :|......|.|..:..||:||||:|||.||.:||.|||:.:::..|
Human   229 ITVCYGLMLLRL-RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRR 292

  Fly   317 --NLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVW--CGSPPPLMTNQQVT 377
              .:....||.:       .:.|.||.:||:|||||.:||::.||::..  ||.|.|...::...
Human   293 DPLVVAALHLCI-------ALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRARE 350

  Fly   378 KTTR 381
            .|.|
Human   351 ATAR 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	50/158 (32%)
		7tm_1	91..347	CDD:278431	85/265 (32%)
OPRD1	NP_000902.3	7tm_4	59..>232	CDD:304433	57/186 (31%)
		7tm_1	66..318	CDD:278431	85/265 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		4/15 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010