DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstA-R1 and CXCR2

DIOPT Version :9

Sequence 1:NP_524700.1 Gene:AstA-R1 / 44126 FlyBaseID:FBgn0266429 Length:394 Species:Drosophila melanogaster
Sequence 2:NP_001161770.1 Gene:CXCR2 / 3579 HGNCID:6027 Length:360 Species:Homo sapiens


Alignment Length:338 Identity:89/338 - (26%)
Similarity:160/338 - (47%) Gaps:44/338 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 NNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQ 104
            :||:::|.....    ..|:...:.||:.:.:.   .|.:.:.::....||||.||:||::.::.
Human    21 SNYSYSSTLPPF----LLDAAPCEPESLEINKY---FVVIIYALVFLLSLLGNSLVMLVILYSRV 78

  Fly   105 MRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMS 169
            .||.|::.::|||::|:||.: .:|..|...| ..|.||...||.|..:..|..:..:..|..:|
Human    79 GRSVTDVYLLNLALADLLFAL-TLPIWAASKV-NGWIFGTFLCKVVSLLKEVNFYSGILLLACIS 141

  Fly   170 FDRFLAVVHPVTSMSLRTERNATLAIMC--AWITIVTTAIPVALSHSVRIYQYHGNAGTACV--F 230
            .||:||:||...::   |::...:..:|  .|...:..|:||.|   .|...|..|...||.  .
Human   142 VDRYLAIVHATRTL---TQKRYLVKFICLSIWGLSLLLALPVLL---FRRTVYSSNVSPACYEDM 200

  Fly   231 STEEEIWSLVGFQV---SFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRM 292
            ......|.:: .::   ||   .::.||.::.|.|...|..|:|:..|         .|.|..|:
Human   201 GNNTANWRML-LRILPQSF---GFIVPLLIMLFCYGFTLRTLFKAHMG---------QKHRAMRV 252

  Fly   293 VVVVVLAFAICWLPIHVILVLKAL--------NLYGGSHLSVIIQIISHVVAYTNSCINPILYAF 349
            :..|||.|.:||||.:::|:...|        .....:|:...:. .:.::...:||:||::|||
Human   253 IFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALD-ATEILGILHSCLNPLIYAF 316

  Fly   350 LSDNFRKAFRKVV 362
            :...||....|::
Human   317 IGQKFRHGLLKIL 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R1NP_524700.1 7tm_4 83..>240 CDD:304433 48/160 (30%)
7tm_1 91..347 CDD:278431 74/270 (27%)
CXCR2NP_001161770.1 7tmA_CXCR1_2 49..325 CDD:341333 82/300 (27%)
TM helix 1 51..75 CDD:341333 9/23 (39%)
TM helix 2 84..105 CDD:341333 7/21 (33%)
TM helix 3 120..142 CDD:341333 4/21 (19%)
TM helix 4 164..180 CDD:341333 3/15 (20%)
TM helix 5 209..232 CDD:341333 5/26 (19%)
TM helix 6 250..272 CDD:341333 9/21 (43%)
TM helix 7 293..318 CDD:341333 7/25 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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