DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and oprd1b

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_997920.2	Gene:	oprd1b / 336529	ZFINID:	ZDB-GENE-030131-8473	Length:	375	Species:	Danio rerio

Alignment Length:	343	Identity:	111/343 - (32%)
Similarity:	177/343 - (51%)	Gaps:	25/343 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ISVSNSSG------NNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLL 90
            ::||:.|.      :|.:|..|......:.:..|.|..|...:....::..:...:.:|...||:
Zfish     6 VTVSDFSERYPLFLHNSSFLEEPAGLLSNWSGGSSELKAVRGSSAVAIAVSITALYSVICVVGLV 70

  Fly    91 GNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIV 155
            ||.||:..||...:|::.||:.|.|||::|.| ....:||.:..|::..||||.:.||.|..:..
Zfish    71 GNVLVMYGVVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSAKYLMGTWPFGELLCKVVIAIDY 134

  Fly   156 VTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQY 220
            .....|::||.:||.||::||.|||.::..||...|.:..:|.||.......||.:   :.:.:.
Zfish   135 YNMFTSIFTLTMMSVDRYIAVCHPVRALDFRTPVKAKIINICVWILSSAVGFPVMV---MAVTKE 196

  Fly   221 HGNAGTACV--FSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESR 283
            ..:..|.|:  |...|..|..| .::..|:.::|.|:.:|...|..|:.|| ||......|.|..
Zfish   197 LDSGKTICMLKFPDPEWYWDTV-TKICVFIFAFVFPVLVITVCYGLMILRL-KSVRLLSGSKEKD 259

  Fly   284 KGKRRVTRMVVVVVLAFAICWLPIHVILVLKAL------NLYGGSHLSVIIQIISHVVAYTNSCI 342
            :..||:||||:|||.||.|||.|||:.:::|.:      ||     |.|....:...:.|.||.:
Zfish   260 RNLRRITRMVLVVVAAFIICWTPIHIFIIVKTVVEIDQKNL-----LVVACWHLCIALGYMNSSL 319

  Fly   343 NPILYAFLSDNFRKAFRK 360
            ||:|||||.:||::.||:
Zfish   320 NPVLYAFLDENFKRCFRE 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	53/158 (34%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	90/263 (34%)
oprd1b	NP_997920.2	7tm_1	76..324	CDD:278431	86/258 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010