Protein Alignment AstA-R1 and npy4r

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_571515.1
• Gene: npy4r / 30717
• ZFINID: ZDB-GENE-980526-393
• Length: 377
• Species: Danio rerio
• Alignment Length: 357
• Identity: 97/357 - (27%)
• Similarity: 169/357 - (47%)
• Gaps: 38/357 - (10%)

  Fly    54 HNANDSMEYDAESVALERIVSTIVPVF-FGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLA 117
            ||.::|..:..:....:....|:..|. :.::...|||||.|:|.:::..:...:.|::||.||:
Zfish    21 HNQSNSSLFLLDVPCWQSSTMTLTLVLCYCLVLILGLLGNILLICIIMHQRDPPNVTSILIANLS 85

  Fly   118 VSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTS 182
            |||||..:||:|||....::..|.||.:.|:.:.::..|:...||.:|||::.:|...::||  |
Zfish    86 VSDILVSVFCLPFTVVYTLMDHWIFGALLCRLMPFVQCVSVTVSVLSLVLIALERHQLILHP--S 148

  Fly   183 MSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIW----SLVGFQ 243
            ....:...|.:|::..|:....|::|....|.:....|..............|:|    ..:.:.
Zfish   149 GWKPSVPQAYIAVLTVWLLACVTSLPFLAFHLLTSEPYSLFPAPLSQLQVCLEVWPSQDHKLAYT 213

  Fly   244 VSFFLSSYVAPLTLICFLYMGMLARLWKS----APGCKPSAESRKGK----RRVTRMVVVVVLAF 300
            .|..|..|..||.|:...|:.:..||.:.    ...|..:.|....:    :|:..|:..:|.||
Zfish   214 TSLLLFQYCCPLLLMLLCYLRIFLRLQRRERMLERQCSRNREDEHRRVMHSKRINVMLATLVAAF 278

  Fly   301 AICWLPIHVILVLKALNLYGGSHLSV-------IIQIISHVVAYTNSCINPILYAFLSDNFRKAF 358
            |:||||      |.|.|:.......|       ::..:.|::|.:::|:|||:|.||:.||||..
Zfish   279 AVCWLP------LNAFNVVADCDQEVLPVCNHNLLFSLCHLLAMSSTCVNPIIYGFLNSNFRKDV 337

  Fly   359 RKVV-WCGSPP--------PLMT-NQQVTKTT 380
            ..|| .|...|        |:.| |..|::|:
Zfish   338 ASVVLHCHFQPLEDSYEHFPMSTMNTDVSRTS 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	85/302 (28%)
		TM helix 1	76..102	CDD:320224	8/26 (31%)
		TM helix 2	109..135	CDD:320224	15/25 (60%)
		TM helix 3	147..177	CDD:320224	8/29 (28%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	7/28 (25%)
		TM helix 6	284..314	CDD:320224	10/33 (30%)
		TM helix 7	326..351	CDD:320224	9/31 (29%)
npy4r	NP_571515.1	7tm_GPCRs	43..337	CDD:475119	84/301 (28%)
		TM helix 1	45..69	CDD:320519	8/23 (35%)
		TM helix 2	78..100	CDD:320519	13/21 (62%)
		TM helix 3	116..138	CDD:320519	6/21 (29%)
		TM helix 4	159..175	CDD:320519	3/15 (20%)
		TM helix 5	210..233	CDD:320519	6/22 (27%)
		TM helix 6	268..290	CDD:320519	11/27 (41%)
		TM helix 7	305..330	CDD:320519	8/24 (33%)