DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and Oxgr1

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_997471.1	Gene:	Oxgr1 / 290493	RGDID:	1303155	Length:	337	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	80/334 - (23%)
Similarity:	164/334 - (49%)	Gaps:	42/334 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 DHNANDS--MEYDAESVALERIVS-------TIVPVFFGIIGFAGLLGNGLVILVVVANQQMRST 108
            |..||||  ::|   ..|||....       ..:||.:.||...|..||.:.|.:.|...:...:
  Rat     6 DSPANDSDFLDY---ITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKS 67

  Fly   109 TNLLIINLAVSDILFVIFCVPFTATDYVLPE-WPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDR 172
            :.::::|||::|:|: :..:||....|...| |.||:..|||:::......:.|:..|...|..|
  Rat    68 STIIMLNLALTDLLY-LTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFR 131

  Fly   173 FLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVA--LSHSVRIYQYHGNAGTACV-FSTEE 234
            ::.::||::..|::..|.|.:|....|:..:...:|:.  ::.:.|..:      :||: .::.:
  Rat   132 YIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNR------SACLDLTSSD 190

  Fly   235 EIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLA 299
            ::.::..:.:....:::..||.::...|..:::.|...     |...| ..|::..|:.::::|.
  Rat   191 DLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHG-----PRTHS-CFKQKARRLTILLLLV 249

  Fly   300 FAICWLPIHVILVLKALNLYGGSHLSVIIQIISHV---------VAYTNSCINPILYAFLSDNFR 355
            |.:|:||.|::.|::..:..    ||:...|.||:         :|..|:..|.:||..:|:||:
  Rat   250 FYVCFLPFHILRVIRIESRL----LSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQ 310

  Fly   356 KAFRKVVWC 364
            :||...|.|
  Rat   311 QAFCSAVRC 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	37/160 (23%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	57/268 (21%)
Oxgr1	NP_997471.1	7tmA_OXGR1	35..313	CDD:320497	67/294 (23%)
		TM helix 1	36..60	CDD:320497	8/23 (35%)
		TM helix 2	69..90	CDD:320497	7/21 (33%)
		TM helix 3	107..129	CDD:320497	4/21 (19%)
		TM helix 4	152..168	CDD:320497	2/15 (13%)
		TM helix 5	196..219	CDD:320497	2/22 (9%)
		TM helix 6	240..262	CDD:320497	7/21 (33%)
		TM helix 7	281..306	CDD:320497	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000