Protein Alignment AstA-R1 and GPR15

DIOPT Version :9

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_005281.1
• Gene: GPR15 / 2838
• HGNCID: 4469
• Length: 360
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 95/328 - (28%)
• Similarity: 149/328 - (45%)
• Gaps: 35/328 - (10%)

  Fly    74 STIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLP 138
            |..:|||:..:...|:|||.:::..:......|...::.|||||.||.:|::....:...:..|.
Human    33 SVFLPVFYTAVFLTGVLGNLVLMGALHFKPGSRRLIDIFIINLAASDFIFLVTLPLWVDKEASLG 97

  Fly   139 EWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCA--WIT 201
            .|..|:..||...|||.|..||||..|..||.||:||:|.||.|...|  |.....::||  |..
Human    98 LWRTGSFLCKGSSYMISVNMHCSVLLLTCMSVDRYLAIVWPVVSRKFR--RTDCAYVVCASIWFI 160

  Fly   202 IVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEE------IWSLVGFQVSFFLSSYVAPLTLICF 260
            .....:|..||..:.:....       .:..|::      |||||....:||:     ||..|..
Human   161 SCLLGLPTLLSRELTLIDDK-------PYCAEKKATPIKLIWSLVALIFTFFV-----PLLSIVT 213

  Fly   261 LYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHL- 324
            .|. .:||  |.....:.|.:..|..::..:::.:||.||.:.|||.:....|..::.....|.
Human   214 CYC-CIAR--KLCAHYQQSGKHNKKLKKSIKIIFIVVAAFLVSWLPFNTFKFLAIVSGLRQEHYL 275

  Fly   325 -SVIIQI---ISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTNQQVTKTTRTATG 385
             |.|:|:   :|..:|:.|||:||.:|.......|:|   :|.|..  |.:.|.....:|.|:..
Human   276 PSAILQLGMEVSGPLAFANSCVNPFIYYIFDSYIRRA---IVHCLC--PCLKNYDFGSSTETSDS 335

  Fly   386 NGT 388
            :.|
Human   336 HLT 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	49/164 (30%)
		7tm_1	91..347	CDD:278431	79/268 (29%)
GPR15	NP_005281.1	7tmA_GPR15	34..313	CDD:320322	87/298 (29%)
		TM helix 1	35..61	CDD:320322	7/25 (28%)
		TM helix 2	68..93	CDD:320322	8/24 (33%)
		TM helix 3	106..136	CDD:320322	17/29 (59%)
		TM helix 4	150..168	CDD:320322	3/17 (18%)
		TM helix 5	192..221	CDD:320322	13/36 (36%)
		TM helix 6	234..264	CDD:320322	8/29 (28%)
		TM helix 7	281..306	CDD:320322	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910