Protein Alignment AstA-R1 and NPBWR2

DIOPT Version :9

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_005277.2
• Gene: NPBWR2 / 2832
• HGNCID: 4530
• Length: 333
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 107/361 - (29%)
• Similarity: 175/361 - (48%)
• Gaps: 56/361 - (15%)

  Fly    20 KASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIVPVFFGII 84
            :.|:.....|:.:|..|.:|:|..|            ::.:.:          :..::|..:..|
Human    13 RGSFSLPTMGANVSQDNGTGHNATF------------SEPLPF----------LYVLLPAVYSGI 55

  Fly    85 GFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKF 149
            ...||.||..||||::...:|::.||:.|:||||:|.||.: .:|....:::|..||||.:.||.
Human    56 CAVGLTGNTAVILVILRAPKMKTVTNVFILNLAVADGLFTL-VLPVNIAEHLLQYWPFGELLCKL 119

  Fly   150 VQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTS--MSLRTERNATLAIMCAWITIVTTAIPVALS 212
            |..:.......|:|.|.:||.||:|.|:..|.|  |..||.|.|.:|.:|.|:.:....:|
Human   120 VLAVDHYNIFSSIYFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVLP---- 180

  Fly   213 HSVRIYQYHGNAGTACVFSTE-------------EEIWSLVGFQVSFFLSSYVAPLTLICFLYMG 264
                .:.:.|      |:|.|             |::| ....:|...:..:|.|:..||.||..
Human   181 ----FFSFAG------VYSNELQVPSCGLSFPWPEQVW-FKASRVYTLVLGFVLPVCTICVLYTD 234

  Fly   265 MLARLWKSAPGCKPSAES-RKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVII 328
            :|.||  .|...:..|:: .|.:|:||.:|:||:....:||.|.|:..|:........:.|.:.:
Human   235 LLRRL--RAVRLRSGAKALGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDLPQTPLVISM 297

  Fly   329 QIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWC 364
            ..:...::|.|||:||.|||||.|||||.||.::.|
Human   298 SYVITSLSYANSCLNPFLYAFLDDNFRKNFRSILRC 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	55/171 (32%)
		7tm_1	91..347	CDD:278431	83/271 (31%)
NPBWR2	NP_005277.2	7tmA_NPBWR	46..327	CDD:320215	97/298 (33%)
		TM helix 1	47..73	CDD:320215	10/25 (40%)
		TM helix 2	80..106	CDD:320215	11/26 (42%)
		TM helix 3	117..147	CDD:320215	11/29 (38%)
		TM helix 4	161..183	CDD:320215	6/29 (21%)
		TM helix 5	209..238	CDD:320215	8/28 (29%)
		TM helix 6	253..283	CDD:320215	12/29 (41%)
		TM helix 7	295..320	CDD:320215	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010