Protein Alignment AstA-R1 and XCR1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_005274.1
• Gene: XCR1 / 2829
• HGNCID: 1625
• Length: 333
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 91/364 - (25%)
• Similarity: 167/364 - (45%)
• Gaps: 82/364 - (22%)

  Fly    37 SSGNNYAFTSEHTDHSDHNANDSMEYDAESVALER---IVSTI-VPVFFGIIGFAGLLGNGLVIL 97
            ||||..:.|..:             ||.:|...|.   :.:|: ..|.:.::....|:||.||:.
Human     3 SSGNPESTTFFY-------------YDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLW 54

  Fly    98 VVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEW--PF------GNVWCKFVQYMI 154
            |:|..:.:.|.||:.|:||.:||::|.  |        :||.|  |:      |:..||.:..:.
Human    55 VLVKYESLESLTNIFILNLCLSDLVFA--C--------LLPVWISPYHWGWVLGDFLCKLLNMIF 109

  Fly   155 VVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQ 219
            .::.:.|::.|.:|:..|:|:||.|::::.:.|.|...|..|..|:..:.::|...:.|.|
Human   110 SISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKV---- 170

  Fly   220 YHGNAGTACVFSTEEEIWSLVG-FQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESR 283
                ..:.|.:|  |..|.|.. :|.:.|   ::..|.:|.|.|:.:|..|::|         ..
Human   171 ----LSSGCDYS--ELTWYLTSVYQHNLF---FLLSLGIILFCYVEILRTLFRS---------RS 217

  Fly   284 KGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQ------------IISHVVA 336
            |.:.|..:::..:|:|:.:.|.|.:..|.|:.|      ..:.||:            :|...:|
Human   218 KRRHRTVKLIFAIVVAYFLSWGPYNFTLFLQTL------FRTQIIRSCEAKQQLEYALLICRNLA 276

  Fly   337 YTNSCINPILYAFLSDNFRKAFRKVV---W-C--GSPPP 369
            :::.|.||:||.|:...||...:.|:   | |  .:|.|
Human   277 FSHCCFNPVLYVFVGVKFRTHLKHVLRQFWFCRLQAPSP 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	77/304 (25%)
		TM helix 1	76..102	CDD:320224	8/26 (31%)
		TM helix 2	109..135	CDD:320224	9/25 (36%)
		TM helix 3	147..177	CDD:320224	7/29 (24%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	8/29 (28%)
		TM helix 6	284..314	CDD:320224	7/29 (24%)
		TM helix 7	326..351	CDD:320224	10/36 (28%)
XCR1	NP_005274.1	7tmA_XCR1	32..298	CDD:341337	76/303 (25%)
		TM helix 1	32..59	CDD:341337	8/26 (31%)
		TM helix 2	66..91	CDD:341337	12/34 (35%)
		TM helix 3	102..132	CDD:341337	7/29 (24%)
		TM helix 4	144..166	CDD:341337	5/21 (24%)
		TM helix 5	182..211	CDD:341337	9/31 (29%)
		TM helix 6	218..248	CDD:341337	7/29 (24%)
		TM helix 7	266..291	CDD:341337	8/24 (33%)