Protein Alignment AstA-R1 and Oprm1

DIOPT Version :9

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001033690.1
• Gene: Oprm1 / 25601
• RGDID: 3234
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 361
• Identity: 117/361 - (32%)
• Similarity: 186/361 - (51%)
• Gaps: 22/361 - (6%)

  Fly    29 GSIISVSNSSGNNYAFTSEHTDHSDHN-----ANDSMEYDAESVALERIVSTIVPVFFGIIGFAG 88
            ||.:::|:..||       .:|....|     .|||:.....|.::  :.:..:...:.|:...|
  Rat    27 GSWLNLSHVDGN-------QSDPCGLNRTGLGGNDSLCPQTGSPSM--VTAITIMALYSIVCVVG 82

  Fly    89 LLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYM 153
            |.||.||:.|:|...:|::.||:.|.|||::|.| ....:||.:.:|::..||||.:.||.|..:
  Rat    83 LFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPFGTILCKIVISI 146

  Fly   154 IVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIY 218
            .......|::||..||.||::||.|||.::..||.|||.:..:|.||......:||....:.:..
  Rat   147 DYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYR 211

  Fly   219 QYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESR 283
            |  |:......||.....|..: .::..|:.:::.|:.:|...|..|:.|| ||......|.|..
  Rat   212 Q--GSIDCTLTFSHPTWYWENL-LKICVFIFAFIMPVLIITVCYGLMILRL-KSVRMLSGSKEKD 272

  Fly   284 KGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQIISHVVAYTNSCINPILYA 348
            :..||:||||:|||..|.:||.|||:.:::|||.....:....:.......:.|||||:||:|||
  Rat   273 RNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYA 337

  Fly   349 FLSDNFRKAFRKVVWCGSPPPLMTNQQVTKTTRTAT 384
            ||.:||::.||:  :| .|......||.:...|..|
  Rat   338 FLDENFKRCFRE--FC-IPTSSTIEQQNSTRVRQNT 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	55/156 (35%)
		7tm_1	91..347	CDD:278431	88/255 (35%)
Oprm1	NP_001033690.1	7tm_4	77..>281	CDD:304433	69/208 (33%)
		7tm_1	85..336	CDD:278431	88/255 (35%)
		NPxxY, plays a role in stabilizing the activated conformation of the receptor. /evidence=ECO:0000250|UniProtKB:P42866	332..336		2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	361..385		3/10 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010