DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and Sstr4

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_037168.1	Gene:	Sstr4 / 25555	RGDID:	3764	Length:	384	Species:	Rattus norvegicus

Alignment Length:	355	Identity:	107/355 - (30%)
Similarity:	177/355 - (49%)	Gaps:	69/355 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 VPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWP 141
            :...:.::...||:||.|||.|::...:|::.||:.::||||:|.||:: .|||.|:...|..||
  Rat    46 IQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFML-SVPFVASAAALRHWP 109

  Fly   142 FGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTA 206
            ||.|.|:.|..:..:....||:.|.::|.||::|||||:.:.:.|....|.|..:..|:..:...
  Rat   110 FGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVT 174

  Fly   207 IPVALSHSVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARL-- 269
            :|:|:....|  ...|....||........||.| |.:..||..::.|:..|...|:.::.::
  Rat   175 LPIAVFADTR--PARGGEAVACNLHWPHPAWSAV-FVIYTFLLGFLLPVLAIGLCYLLIVGKMRA 236

  Fly   270 ------WKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVII 328
                  |:         :.|:.::::||:|::||..|.:||:|.:|:   :.|||:..| |...:
  Rat   237 VALRAGWQ---------QRRRSEKKITRLVLMVVTVFVLCWMPFYVV---QLLNLFVTS-LDATV 288

  Fly   329 QIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWC---------------------------GS 366
            ..:|.:::|.|||.|||||.|||||||::|::|: |                           |.
  Rat   289 NHVSLILSYANSCANPILYGFLSDNFRRSFQRVL-CLRCCLLETTGGAEEEPLDYYATALKSRGG 352

  Fly   367 P----PPLMTNQQ------------VTKTT 380
            |    |||...|:            .||||
  Rat   353 PGCICPPLPCQQEPMQAEPACKRVPFTKTT 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	53/156 (34%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	83/263 (32%)
Sstr4	NP_037168.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		7tm_4	52..283	CDD:304433	75/246 (30%)
		7tm_1	60..307	CDD:278431	83/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010