Protein Alignment AstA-R1 and Oprd1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_036749.1
• Gene: Oprd1 / 24613
• RGDID: 3233
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 389
• Identity: 119/389 - (30%)
• Similarity: 186/389 - (47%)
• Gaps: 62/389 - (15%)

  Fly     7 LALLLATLISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALER 71
            ||.:..|..|::|.||..|:|:....|.|:.                          |.::|:..
  Rat    16 LANVSDTFPSAFPSASANASGSPGARSASSL--------------------------ALAIAITA 54

  Fly    72 IVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYV 136
            :.|.:..|        |||||.||:..:|...::::.||:.|.|||::|.| ....:||.:..|:
  Rat    55 LYSAVCAV--------GLLGNVLVMFGIVRYTKLKTATNIYIFNLALADAL-ATSTLPFQSAKYL 110

  Fly   137 LPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWIT 201
            :..||||.:.||.|..:.......|::||.:||.||::||.|||.::..||...|.|..:|.|:.
  Rat   111 METWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVL 175

  Fly   202 IVTTAIPVALSHSVRIYQYHGNAGTACV--FSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMG 264
            .....:|:.:   :.:.|....| ..|.  |.:....|..| .::..||.::|.|:.:|...|..
  Rat   176 ASGVGVPIMV---MAVTQPRDGA-VVCTLQFPSPSWYWDTV-TKICVFLFAFVVPILIITVCYGL 235

  Fly   265 MLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKAL--------NLYGG 321
            ||.|| :|......|.|..:..||:||||:|||.||.:||.|||:.:::..|        .:...
  Rat   236 MLLRL-RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAA 299

  Fly   322 SHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKV--VWCGSPPP--LMTNQQVTKTTR 381
            .||.:       .:.|.||.:||:|||||.:||::.||::  ..||...|  |...:|.|...|
  Rat   300 LHLCI-------ALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARER 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	96/292 (33%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	11/29 (38%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	9/28 (32%)
		TM helix 6	284..314	CDD:320224	16/29 (55%)
		TM helix 7	326..351	CDD:320224	9/24 (38%)
Oprd1	NP_036749.1	7tmA_Delta_opioid_R	50..329	CDD:320217	98/300 (33%)
		TM helix 1	51..77	CDD:320217	11/33 (33%)
		TM helix 2	84..110	CDD:320217	10/26 (38%)
		TM helix 3	121..151	CDD:320217	11/29 (38%)
		TM helix 4	163..185	CDD:320217	5/21 (24%)
		TM helix 5	209..239	CDD:320217	10/30 (33%)
		TM helix 6	258..284	CDD:320217	15/25 (60%)
		TM helix 7	297..322	CDD:320217	11/31 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		5/17 (29%)