Protein Alignment AstA-R1 and Agtr1a

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_112247.2
• Gene: Agtr1a / 24180
• RGDID: 2070
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 343
• Identity: 90/343 - (26%)
• Similarity: 165/343 - (48%)
• Gaps: 28/343 - (8%)

  Fly    63 DAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFC 127
            |.........:..::|..:.||...|:.||.||::|:....::::..::.::|||::|:.|:: .
  Rat    17 DCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLL-T 80

  Fly   128 VP----FTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTE 188
            :|    :||.:|   .|||||..||.....:....:.||:.|..:|.||:||:|||:.|...||.
  Rat    81 LPLWAVYTAMEY---RWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTM 142

  Fly   189 RNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIWSL-VGFQVSFFLSSYV 252
            ..|.:..:..|:.....::|..:..:|  |.......|.|.|..|....:| :|..::..:..::
  Rat   143 LVAKVTCIIIWLMAGLASLPAVIHRNV--YFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFL 205

  Fly   253 APLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRR---VTRMVVVVVLAFAICWLPIHVILVLK 314
            .|..:|...|    ..:||:   .|.:.|.:|.|.|   :.|:::.:||.|...|:|..:...|.
  Rat   206 FPFLIILTSY----TLIWKA---LKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLD 263

  Fly   315 ALNLYGGSH---LSVIIQI---ISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTN 373
            .|...|..|   :|.|:..   |:..:||.|:|:||:.|.||...|:|.|.:::.. .||...::
  Rat   264 VLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKY-IPPKAKSH 327

  Fly   374 QQVTKTTRTATGNGTSNI 391
            ..::....|.:...:.|:
  Rat   328 SSLSTKMSTLSYRPSDNM 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	84/296 (28%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	8/29 (28%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	2/19 (11%)
		TM helix 5	239..268	CDD:320224	5/29 (17%)
		TM helix 6	284..314	CDD:320224	9/32 (28%)
		TM helix 7	326..351	CDD:320224	10/27 (37%)
Agtr1a	NP_112247.2	7tmA_AT1R	29..313	CDD:320320	84/296 (28%)
		TM helix 1	30..56	CDD:320320	9/25 (36%)
		TM helix 2	63..88	CDD:320320	6/25 (24%)
		TM helix 3	101..131	CDD:320320	10/29 (34%)
		TM helix 4	144..165	CDD:320320	3/20 (15%)
		TM helix 5	192..221	CDD:320320	5/32 (16%)
		TM helix 6	233..263	CDD:320320	7/29 (24%)
		TM helix 7	281..306	CDD:320320	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	337..359		1/9 (11%)