Protein Alignment AstA-R1 and Mchr1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_660114.1
• Gene: Mchr1 / 207911
• MGIID: 2180756
• Length: 353
• Species: Mus musculus
• Alignment Length: 386
• Identity: 113/386 - (29%)
• Similarity: 168/386 - (43%)
• Gaps: 42/386 - (10%)

  Fly    10 LLATLISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVS 74
            |.|:|:|:.|.||          ::|:...|   ||..    .......|:.|          ::
Mouse     3 LQASLLSTGPNAS----------NISDGQDN---FTLA----GPPPRTRSVSY----------IN 40

  Fly    75 TIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTN---LLIINLAVSDILFVIFCVPFTATDYV 136
            .|:|..||.|...|::||..||..||...::...:|   :.||||:|.|:||:: .:||.....:
Mouse    41 IIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLL-GMPFMIHQLM 104

  Fly   137 -LPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWI 200
             ...|.||...|..:..|...:...|.|.|..|:.||:||.|||::|...|....|||.|...|.
Mouse   105 GNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWA 169

  Fly   201 TIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGM 265
            ....:..||.|  ..|:..:.|.| ..|..........|..|.:..|..::..|..:|...|:.:
Mouse   170 LSFISITPVWL--YARLIPFPGGA-VGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKI 231

  Fly   266 LARLWKS-APGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQ 329
            |.|:..| ||..:.|...|  .:||||..:.:.|.|.:||.|.:| |.|..|::...:...|.:.
Mouse   232 LQRMTSSVAPASQRSIRLR--TKRVTRTAIAICLVFFVCWAPYYV-LQLTQLSISRPTLTFVYLY 293

  Fly   330 IISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMT--NQQVTKTTRTATGNGT 388
            ..:..:.|.|||:||.:|..|.:.|||.....|...:...|.|  |.|.....||.: .||
Mouse   294 NAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTES-KGT 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	91/287 (32%)
		TM helix 1	76..102	CDD:320224	12/25 (48%)
		TM helix 2	109..135	CDD:320224	11/28 (39%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	7/28 (25%)
		TM helix 6	284..314	CDD:320224	11/29 (38%)
		TM helix 7	326..351	CDD:320224	8/24 (33%)
Mchr1	NP_660114.1	7tmA_MCHR1	41..322	CDD:320460	91/287 (32%)
		TM helix 1	42..68	CDD:320460	12/25 (48%)
		TM helix 2	78..104	CDD:320460	10/26 (38%)
		TM helix 3	116..146	CDD:320460	10/29 (34%)
		TM helix 4	158..178	CDD:320460	5/19 (26%)
		TM helix 5	205..234	CDD:320460	7/28 (25%)
		TM helix 6	249..279	CDD:320460	13/32 (41%)
		TM helix 7	290..315	CDD:320460	8/24 (33%)