DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstA-R1 and Sstr2

DIOPT Version :9

Sequence 1:NP_524700.1 Gene:AstA-R1 / 44126 FlyBaseID:FBgn0266429 Length:394 Species:Drosophila melanogaster
Sequence 2:NP_001036071.1 Gene:Sstr2 / 20606 MGIID:98328 Length:369 Species:Mus musculus


Alignment Length:348 Identity:111/348 - (31%)
Similarity:181/348 - (52%) Gaps:42/348 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 NGSIISVSNSSGNNYAFTSEHTDHSDHNANDSME--YDAESVALERIVSTIVPVFFGIIGFAGLL 90
            |||.:.||:....|.:.       ...|.::..|  ||..|       :.::...:.::...||.
Mouse     9 NGSQVWVSSPFDLNGSL-------GPSNGSNQTEPYYDMTS-------NAVLTFIYFVVCVVGLC 59

  Fly    91 GNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIV 155
            ||.|||.|::...:|::.||:.|:|||::|.||:: .:||.|....|..||||...|:.|..:..
Mouse    60 GNTLVIYVILRYAKMKTITNIYILNLAIADELFML-GLPFLAMQVALVHWPFGKAICRVVMTVDG 123

  Fly   156 VTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQY 220
            :....|::.|.:||.||:||||||:.|...|..|.|.:..:..|...:...:|:.:...:|..|:
Mouse   124 INQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQW 188

  Fly   221 HGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKG 285
             |.:.....:..|...| ..||.:..|:..::.|||:||..|:.::.:: ||:.....|::.:|.
Mouse   189 -GRSSCTINWPGESGAW-YTGFIIYAFILGFLVPLTIICLCYLFIIIKV-KSSGIRVGSSKRKKS 250

  Fly   286 KRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQ-----------IISHVVAYTN 339
            :::|||||.:||..|..||||.::..|         |.:||.|.           ::  ::.|.|
Mouse   251 EKKVTRMVSIVVAVFIFCWLPFYIFNV---------SSVSVAISPTPALKGMFDFVV--ILTYAN 304

  Fly   340 SCINPILYAFLSDNFRKAFRKVV 362
            ||.||||||||||||:|:|:.|:
Mouse   305 SCANPILYAFLSDNFKKSFQNVL 327

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R1NP_524700.1 7tm_4 83..>240 CDD:304433 51/156 (33%)
7tm_1 91..347 CDD:278431 86/266 (32%)
Sstr2NP_001036071.1 7tmA_SSTR2 44..323 CDD:320637 98/293 (33%)
TM helix 1 45..71 CDD:320637 8/25 (32%)
TM helix 2 78..104 CDD:320637 12/26 (46%)
TM helix 3 115..145 CDD:320637 10/29 (34%)
TM helix 4 157..179 CDD:320637 4/21 (19%)
TM helix 5 205..234 CDD:320637 9/28 (32%)
TM helix 6 249..279 CDD:320637 14/38 (37%)
TM helix 7 291..316 CDD:320637 11/26 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24229
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.010

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