Protein Alignment AstA-R1 and Gpr149

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_620246.1
• Gene: Gpr149 / 192251
• RGDID: 619890
• Length: 730
• Species: Rattus norvegicus
• Alignment Length: 396
• Identity: 70/396 - (17%)
• Similarity: 126/396 - (31%)
• Gaps: 135/396 - (34%)

  Fly    44 FTSEHTDHS-----DHNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQ 103
            |.|..|:.|     .||:.|.|. ..|::.|.......:.....::|       .:..||.:...
  Rat     4 FLSNLTNDSRLWKVSHNSTDLMN-SPETLTLSLFCLICLMTLVALVG-------SIFSLVSLLTM 60

  Fly   104 QMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWP-----FGNVWCKFVQYMIVVTCHCSVY 163
            |.|:..::|:.:.:|.|:|.|:     :...:::.:||     :....|.....:.:.....|..
  Rat    61 QYRTVVSMLVTSWSVDDLLSVL-----SVAIFMVLQWPREAPGYFQSLCTTSALLYMCQGLSSNL 120

  Fly   164 TLVLMSFDRFLAVVHPVTSMSLRTERNATLAI---------------MCAWITIVTT-------- 205
            ...|:.|..|..:...|.|.|........|.:               :|.|...|.|
  Rat   121 KATLIVFYNFYTMHRTVVSQSSSWRSGQVLGVALTVWAVSLLLASLPLCGWGVFVRTPWGCLTDC 185

  Fly   206 --------------------AIPVALSHSVRIYQ----YHGN---------------AG--TACV 229
                                .:.|.|:|.:...:    .|.|               ||  ..|:
  Rat   186 SSPYVLLLFAVYASAFGLLAVLSVPLTHQLLCSEEPPRLHANYQEISRGASTPGTPAAGGRVLCL 250

  Fly   230 FSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRR------ 288
            ...:.||.:|.|...|  |||.:.                  .|||...::.:..|||.
  Rat   251 LPEDVEIPALPGTGSS--LSSDMV------------------FAPGQPAASSAGAGKRENLWTPR 295

  Fly   289 ----------VTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHL----SVIIQIISHVVAYTN 339
                      ..|..:::.|...|.|||:.:.:|:|        |:    |:.:.::|.::....
  Rat   296 GSSSFPVSLAQKRFALILALTKVILWLPMMIHMVVK--------HVVGFQSLPVDMLSFLLTLLA 352

  Fly   340 SCINPI 345
            |.:.|:
  Rat   353 STVTPV 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	60/360 (17%)
		TM helix 1	76..102	CDD:320224	3/25 (12%)
		TM helix 2	109..135	CDD:320224	5/25 (20%)
		TM helix 3	147..177	CDD:320224	5/29 (17%)
		TM helix 4	189..209	CDD:320224	5/62 (8%)
		TM helix 5	239..268	CDD:320224	6/28 (21%)
		TM helix 6	284..314	CDD:320224	10/45 (22%)
		TM helix 7	326..351	CDD:320224	3/20 (15%)
Gpr149	NP_620246.1	7tmA_GPR149	35..372	CDD:320139	60/364 (16%)
		TM helix 1	35..60	CDD:320139	3/31 (10%)
		TM helix 2	66..91	CDD:320139	5/29 (17%)
		TM helix 3	104..134	CDD:320139	5/29 (17%)
		TM helix 4	149..169	CDD:320139	1/19 (5%)
		TM helix 5	195..220	CDD:320139	3/24 (13%)
		TM helix 6	301..331	CDD:320139	7/29 (24%)
		TM helix 7	339..364	CDD:320139	3/20 (15%)