Protein Alignment AstA-R1 and npr-22

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001023541.1
• Gene: npr-22 / 190424
• WormBaseID: WBGene00022004
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 310
• Identity: 83/310 - (26%)
• Similarity: 158/310 - (50%)
• Gaps: 47/310 - (15%)

  Fly    79 VFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVL---PEW 140
            :|:.|:....:.||.|||||:|..:::|:.||:||:||||:|:|..:||:||:....::   ..|
 Worm    55 LFYSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVADLLISVFCIPFSYWQVLIYDDQRW 119

  Fly   141 PFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTT 205
            .||::.|..:.::..:....|.:|||::||||::|::..:|.....|.|.|...:...||..:..
 Worm   120 LFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRRALYLVAATWIFSILM 184

  Fly   206 AIPVALSHSVRIYQ-------------YHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTL 257
            |:|  |..:.|.::             |.|::|        |::..:....|  .:..||.|..:
 Worm   185 ALP--LLFTTRFFEDQDGLPNCGENWTYFGDSG--------EQVRKVYSSMV--LILQYVVPQAV 237

  Fly   258 ICFLYMGMLARLWKS-APGCKPSA------ESRKGKRRVTRMVVVVVLAFAICWLPIHVIL---- 311
            :...|..:..::|.| .||.:..|      :..:..:::..||:::...||:||||:.:::
 Worm   238 LIITYTHIGIKMWNSRVPGMQNGATKKMIVDRHESVKKLVPMVILISALFALCWLPLLILINVIP 302

  Fly   312 -VLKALNLYGGSHLSVIIQI--ISHVVAYTNSCINPILYAFLSDNFRKAF 358
             ....:|.:|     .|:.:  .:|.:|.::|.:|||:|...:..||:.|
 Worm   303 EFYPDINSWG-----YILYLWWFAHGLAMSHSMVNPIIYFIRNARFREGF 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	82/308 (27%)
		TM helix 1	76..102	CDD:320224	10/22 (45%)
		TM helix 2	109..135	CDD:320224	14/25 (56%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	5/28 (18%)
		TM helix 6	284..314	CDD:320224	8/34 (24%)
		TM helix 7	326..351	CDD:320224	8/26 (31%)
npr-22	NP_001023541.1	7tmA_PR4-like	51..347	CDD:320514	82/308 (27%)
		TM helix 1	52..78	CDD:320514	10/22 (45%)
		TM helix 2	85..110	CDD:320514	14/24 (58%)
		TM helix 3	126..156	CDD:320514	10/29 (34%)
		TM helix 4	169..190	CDD:320514	6/22 (27%)
		TM helix 5	219..248	CDD:320514	5/30 (17%)
		TM helix 6	271..301	CDD:320514	8/29 (28%)
		TM helix 7	315..340	CDD:320514	7/24 (29%)