DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AstA-R1 and srx-62

DIOPT Version :9

Sequence 1:NP_524700.1 Gene:AstA-R1 / 44126 FlyBaseID:FBgn0266429 Length:394 Species:Drosophila melanogaster
Sequence 2:NP_504114.1 Gene:srx-62 / 187212 WormBaseID:WBGene00005953 Length:300 Species:Caenorhabditis elegans


Alignment Length:270 Identity:56/270 - (20%)
Similarity:109/270 - (40%) Gaps:47/270 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 IGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDIL----FVIFCVPFTATD-YVLPEWPFG 143
            |.|.|.:.|..:...:...:....:...|..|.|:.|.|    |:::..|....| .::.|.   
 Worm    18 ISFLGSILNWTIFYAIQRLECFNHSFGFLSANQALVDGLHSTTFLLYFCPMVLLDNAIMKEM--- 79

  Fly   144 NVWCKFVQYMIVVTCH-CSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAI 207
            :..|.||    ::.|: .||...:.:|.:||.||..|....::..|:|:.:.|:..|:...:.||
 Worm    80 SHHCGFV----LLLCYELSVMIHLAISLNRFCAVWIPYQYHNIFNEKNSKILIILIWLFTGSVAI 140

  Fly   208 PVALSHSVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSS-YVAPLTLICFLYMGMLAR--- 268
            .:   :.:..:.|:.:......| |:.::.:.:|:...|..:: .||.:.||..|.:..:.|   
 Worm   141 YL---YEILCHIYYEDKSDFLTF-TDSKLCANIGWYGDFVKNACIVAVIMLIDILTVIKVRRMSR 201

  Fly   269 -----LWKSAPGCKPSAESRKGKRRVTRMVV-------------------VVVLAFAICWLPIHV 309
                 :.:.|.....|.|.|..|:.||:..|                   :|....:..|:.:|.
 Worm   202 KISVNITEQAQNKLSSREMRFLKQTVTQGSVFLLELLTYFFIPQYFSNKWIVFFGTSFAWVAVHA 266

  Fly   310 I--LVLKALN 317
            :  ||:...|
 Worm   267 VDGLVVVIFN 276

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R1NP_524700.1 7tm_4 83..>240 CDD:304433 34/161 (21%)
7tm_1 91..347 CDD:278431 53/263 (20%)
srx-62NP_504114.1 7TM_GPCR_Srx 17..276 CDD:370981 55/268 (21%)
TM helix 2 43..69 CDD:341315 7/25 (28%)
TM helix 3 80..110 CDD:341315 10/33 (30%)
TM helix 4 123..141 CDD:341315 4/17 (24%)
TM helix 5 167..191 CDD:341315 6/23 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.