DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and srx-65

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_504086.2	Gene:	srx-65 / 187096	WormBaseID:	WBGene00005956	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	173	Identity:	33/173 - (19%)
Similarity:	65/173 - (37%)	Gaps:	30/173 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDIL----FVIFCVP 129
            :::|:..:||     |...|.:.|......:......:.:...|..|.|::|.|    |:::..|
Worm     4 VDQILLVLVP-----ISIVGAVLNWSSFYSICKLTSYKHSFGYLSANQALADALHSTIFLLYFCP 63

  Fly   130 FTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLA 194
            ....|:     .|...:..|..::::.....|:.|.:.:||.||.::..||............:.
Worm    64 MALLDH-----SFLKQYSHFCGFILLFFYELSIMTHLAVSFKRFFSIWFPVIFKKHFDVPRTKVV 123

  Fly   195 IMCAW-ITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEI 236
            |...| .|::...:         :|:      ..|.|..:|||
Worm   124 IGVLWCYTLIQATV---------LYE------VLCYFYFDEEI 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	30/159 (19%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	28/151 (19%)
srx-65	NP_504086.2	TM helix 1	7..32	CDD:341315	6/29 (21%)
		7TM_GPCR_Srx	13..272	CDD:370981	31/164 (19%)
		TM helix 2	39..65	CDD:341315	7/25 (28%)
		TM helix 3	77..106	CDD:341315	7/28 (25%)
		TM helix 4	119..138	CDD:341315	3/27 (11%)
		TM helix 5	163..188	CDD:341315
		TM helix 6	213..243	CDD:341315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910