DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AstA-R1 and H09F14.1

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001256232.1	Gene:	H09F14.1 / 186709	WormBaseID:	WBGene00010375	Length:	401	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	75/324 - (23%)
Similarity:	143/324 - (44%)	Gaps:	75/324 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 IIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSD------ILFVIFCVPFTATDYVLPEWP 141
            :|...||.||.:.::.:..::..|...|:.:|.|.::|      ||.:.|.|.:.|.:|
Worm    17 LIVIFGLSGNVISLVTIFHSRLRRVNANIYLIVLTLADSIFLTGILLICFKVDWIAYEY------ 75

  Fly   142 FGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTA 206
                 |..::|:::...:.|.::...::.:|:||:.||::.|.......|  .:|..|:     .
Worm    76 -----CVGLEYVLMTASYISSWSTAALTIERYLAIAHPLSHMKYGHVDRA--KVMLYWV-----P 128

  Fly   207 IPVALSHSVRIYQYHGNAGTACVFSTE-----------EEIWSLVGFQVSFFLSSYVAPLTLICF 260
            ||..|    :::|:         ||.|           |..:.::...|...| .||.|..:|..
Worm   129 IPFVL----QLFQF---------FSLEPATEERKCALKEANYQIIAQAVDTVL-CYVVPCGIIVV 179

  Fly   261 LYMGMLARLWKSAPGCKPSAESRKGKRR-----------VTRMVVVVVLAFAICWLPIHVILVLK 314
            |.:.:..::.||....  .||::|...|           .||::.|:.|.|.:...|.:||::::
Worm   180 LNILVALQVQKSQEHF--MAETKKSNSRRTGGSSSSSGTWTRILWVMPLVFVVLNTPFYVIMMIE 242

  Fly   315 AL--NLYGG-------SHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRK----AFRKVVWCG 365
            .:  .:|..       |.|.|.:...:|.:.|.|:.|:.::|||.|.||||    |:::::..|
Worm   243 IVFQIIYQSPPSGDTRSELFVTVYNTAHYMYYMNTAIDVLVYAFSSANFRKTAVIAWKRILCPG 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	36/173 (21%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	62/292 (21%)
H09F14.1	NP_001256232.1	7tm_GPCRs	10..295	CDD:391938	73/311 (23%)
		TM helix 1	10..36	CDD:341315	5/18 (28%)
		TM helix 2	43..67	CDD:341315	6/23 (26%)
		TM helix 3	77..106	CDD:341315	5/28 (18%)
		TM helix 5	158..183	CDD:341315	7/25 (28%)
		TM helix 6	212..242	CDD:341315	8/29 (28%)
		TM helix 7	263..288	CDD:341315	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910